Synthesis, biological evaluation and molecular modeling of 1,2,3-triazole analogs of combretastatin A-1

Øyvind W. Akselsen, Kristin Odlo, Jing‐Jy Cheng, +3

Bioorganic & Medicinal Chemistry

1,2,3-Triazole AnalogsMedicineMolecular BiologyBiological EvaluationPharmacology +2

Raft component GD3 associates with tubulin following CD95/Fas ligation

Maurizio Sorice, Paola Matarrese, Antonella Tinari, +9

The FASEB Journal

MitophagyProtein FunctionGanglioside RedistributionAutophagyImmunology +11

Possible binding site for paclitaxel at microtubule pores

Matteo Magnani, Giorgio Maccari, José M. Andreu, +1

FEBS Journal

Molecular BiologyMicrotubule WallCytoskeletonAnalytical UltracentrifugationCellular Physiology +17

Identification, synthesis and biological activity of alkyl-guanidine oligomers as potent antibacterial agents

Claudio Zamperini, Giorgio Maccari, Davide Deodato, +7

Scientific Reports

Discovery of in vitro antitubercular agents through in silico ligand-based approaches

Daniela De Vita, Fabiana Pandolfi, Roberto Cirilli, +12

European Journal of Medicinal Chemistry

Vitro Antitubercular AgentsBiochemistryMedicineRational Drug DesignMechanism Of Action +6

Probing the Pore Drug Binding Site of Microtubules with Fluorescent Taxanes: Evidence of Two Binding Poses

Isabel Barasoaı́n, Ana M. García-Carril, Ruth Matesanz, +8

Chemistry & Biology

Molecular BiologyFluorescent TaxanesBiochemical InteractionCytoskeletonBiomolecular Interaction +7

A fast virtual screening approach to identify structurally diverse inhibitors of trypanothione reductase

Giorgio Maccari, Timo Jaeger, Francesca Moraca, +3

Bioorganic & Medicinal Chemistry Letters

Medicinal ChemistryBioorganic ChemistryHit IdentificationBiochemistryAfrican Trypanosomiasis +10

Biological Characterization and in Vivo Assessment of the Activity of a New Synthetic Macrocyclic Antifungal Compound

Davide Deodato, Giorgio Maccari, Filomena De Luca, +13

Journal of Medicinal Chemistry

Fungicidal EffectAntifungal AgentBiochemistryAntifungal AgentsMedicine +13

Synthesis of linear and cyclic guazatine derivatives endowed with antibacterial activity

Giorgio Maccari, Stefania Sanfilippo, Filomena De Luca, +8

Bioorganic & Medicinal Chemistry Letters

DerivativesEngineeringCyclic Guazatine DerivativesMedicineAntibacterial Activity +6

Identification of novel nt-MGAM inhibitors for potential treatment of type 2 diabetes: Virtual screening, atom based 3D-QSAR model, docking analysis and ADME study

Aicha Laoud, Fouad Ferkous, Laura Maccari, +3

Computational Biology and Chemistry

Medicinal ChemistryVirtual ScreeningDrug TargetBiochemistryMedicine +9