Thymic stromal lymphopoietin as a key initiator of allergic airway inflammation in mice

Baohua Zhou, Michael R. Comeau, Thibaut De Smedt, +7

Nature Immunology

AsthmaInflammationKey InitiatorInflammatory Lung DiseaseAllergy +7

Toll-Like Receptor 4 Is Required for Optimal Development of Th2 Immune Responses: Role of Dendritic Cells

Karim Dabbagh, Martin E. Dahl, Pamela Stepick‐Biek, +1

The Journal of Immunology

Viral-induced T helper type 1 responses enhance allergic disease by effects on lung dendritic cells

Martin E. Dahl, Karim Dabbagh, Denny Liggitt, +2

Nature Immunology

AsthmaLung Dendritic CellsInflammatory Lung DiseaseAllergyAllergic Disease +9

Thymic stromal lymphopoietin receptor blockade reduces allergic inflammation in a cynomolgus monkey model of asthma

Donavan T. Cheng, Jens Niewoehner, Martin E. Dahl, +14

Journal of Allergy and Clinical Immunology

InflammationAsthmaAllergyClinical AllergyAllergy Medicine +7

Chemotactic Responses of IL-4-, IL-10-, and IFN-γ-Producing CD4+ T Cells Depend on Tissue Origin and Microbial Stimulus

Gudrun F. Debes, Martin E. Dahl, Azita J. Mahiny, +7

The Journal of Immunology

Discovery of a Potent (4<i>R</i>,5<i>S</i>)-4-Fluoro-5-methylproline Sulfonamide Transient Receptor Potential Ankyrin 1 Antagonist and Its Methylene Phosphate Prodrug Guided by Molecular Modeling

Huifen Chen, Matthew Volgraf, Steven Do, +27

Journal of Medicinal Chemistry

Drug TargetMolecular PainPharmacotherapyPharmacodynamic ModelingMolecular Pharmacology +16

Association of Lyn tyrosine kinase to the GM‐CSF and IL‐3 receptor common βc subunit and role of Src tyrosine kinases in DNA synthesis and anti‐apoptosis

Martin E. Dahl, Ken‐ichi Arai, Sumiko Watanabe

Genes to Cells

TAK-079 is a high affinity monoclonal antibody that effectively mediates CD38+ cell depletion

Glennda Smithson, Jonathan Zalevsky, Wouter Korver, +6

The Journal of Immunology

Clinical ImmunologyCd38+ Cell DepletionImmunologyImmune RegulationImmunologic Mechanism +17

A Novel CCR5-Specific Pharmacodynamic Assay in Whole Blood Using Phosphoflow Cytometry Highlights Different Ligand-Dependent Responses but Similar Properties of Antagonists in CD8+ and CD4+ T Lymphocytes

Martin E. Dahl, Amy E. Berson, José M. Lora, +1

Journal of Pharmacology and Experimental Therapeutics