Katrin Groebke Zbinden

TAAR1 activation modulates monoaminergic neurotransmission, preventing hyperdopaminergic and hypoglutamatergic activity

Florent G. Revel, Jean‐Luc Moreau, Raul R. Gainetdinov et al. · Proceedings of the National Academy of Sciences · 2011 · 362 citations · Full text

A new perspective for schizophrenia: TAAR1 agonists reveal antipsychotic- and antidepressant-like activity, improve cognition and control body weight

F. Revel, J‐L Moreau, Bruno Pouzet et al. · Molecular Psychiatry · 2012 · 285 citations

Psychoactive Drug, Psychiatry, Psychotic Disorder +13

Trace Amine-Associated Receptor 1 Partial Agonism Reveals Novel Paradigm for Neuropsychiatric Therapeutics

Florent G. Revel, Jean‐Luc Moreau, Raul R. Gainetdinov et al. · Biological Psychiatry · 2012 · 196 citations

Psychiatry, Functional Selectivity, Psychotropic Medication +11

Discovery and Characterization of 2-Aminooxazolines as Highly Potent, Selective, and Orally Active TAAR1 Agonists

Guido Galley, Angélica Beurier, Guillaume Décoret et al. · ACS Medicinal Chemistry Letters · 2015 · 50 citations · Full text

Drug Target, Active Taar1 Agonists, Pharmacotherapy +17

Discovery of a factor Xa inhibitor (3R,4R)-1-(2,2-difluoro-ethyl)-pyrrolidine-3,4-dicarboxylic acid 3-[(5-chloro-pyridin-2-yl)-amide] 4-{[2-fluoro-4-(2-oxo-2H-pyridin-1-yl)-phenyl]-amide} as a clinical candidate

Lilli Anselm, David W. Banner, Jörg Benz et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 40 citations · Full text

Medicinal Chemistry, Pharmaceutical Science, Biochemistry +11