Membrane-Proximal Epitope Facilitates Efficient T Cell Synapse Formation by Anti-FcRH5/CD3 and Is a Requirement for Myeloma Cell Killing

Ji Li, Nicola J. Stagg, Jennifer Johnston, +21

Cancer Cell

Synapse FormationImmunologyImmunoeditingCell DeathImmunologic Mechanism +14

Use of a Peptide Derived from Foot-and-Mouth Disease Virus for the Noninvasive Imaging of Human Cancer: Generation and Evaluation of 4-[18F]Fluorobenzoyl A20FMDV2 for <i>In vivo</i> Imaging of Integrin αvβ6 Expression with Positron Emission Tomography

Sven H. Hausner, Danielle DiCara, John F. Marshall, +1

Cancer Research

Antibody-Mediated Targeting of Tau In Vivo Does Not Require Effector Function and Microglial Engagement

Seung-Hye Lee, Claire E. Le Pichon, Oskar Adolfsson, +20

Cell Reports

Tau AntibodiesTau PathologyImmunologyCell DeathImmunologic Mechanism +20

Antibody semorinemab reduces tau pathology in a transgenic mouse model and engages tau in patients with Alzheimer’s disease

Gai Ayalon, Seung-Hye Lee, Oskar Adolfsson, +40

Science Translational Medicine

ImmunologyNeurochemical BiomarkersTransgenic Mouse ModelAlzheimer ’Alzheimer's Disease +19

Structure-Function Analysis of Arg-Gly-Asp Helix Motifs in αvβ6 Integrin Ligands

Danielle DiCara, Chiara Rapisarda, Julie L. Sutcliffe, +5

Journal of Biological Chemistry

BiochemistryProtein AssemblyNatural SciencesMedicineMolecular Biology +5

Foot-and-Mouth Disease Virus Forms a Highly Stable, EDTA-Resistant Complex with Its Principal Receptor, Integrin αvβ6: Implications for Infectiousness

Danielle DiCara, Alison Burman, Stuart Clark, +5

Journal of Virology

Highly StableVirus StructureMolecular VirologyFoot-and-mouth Disease VirusProtein Folding +12

Targeted delivery of cytokine therapy to rheumatoid tissue by a synovial targeting peptide

Sarah E. Wythe, Danielle DiCara, Taher E.I. Taher, +7

Annals of the Rheumatic Diseases

Immune repertoire mining for rapid affinity optimization of mouse monoclonal antibodies

Yi-Chun Hsiao, Yonglei Shang, Danielle DiCara, +11

mAbs

Artificial Immune SystemImmunologyImmunodominanceImmunological ComputingImmunotherapy +16

Development of T-cell engagers selective for cells co-expressing two antigens

Danielle DiCara, Sunil Bhakta, Mary Ann T. Go, +9

mAbs

High-throughput screening of antibody variants for chemical stability: identification of deamidation-resistant mutants

Danielle DiCara, Nisana Andersen, Ruby L.Y. Chan, +6

mAbs

Immunocytochemical TechniqueImmunologyMolecular BiologyAntibody VariantsImmunotherapy +16