TP53 gain-of-function mutation promotes inflammation in glioblastoma

Seok Won Ham, Hee-Young Jeon, Xiong Jin, +11

Cell Death and Differentiation

Neuro-oncologyGliomaMedicineTumor SuppressorCancer Genetics +4

Frizzled 4 Regulates Stemness and Invasiveness of Migrating Glioma Cells Established by Serial Intracranial Transplantation

Xun Jin, Hee-Young Jeon, Kyeung Min Joo, +12

Cancer Research

Gbm RecurrenceRegulates StemnessImmunologyMigrating Glioma CellsStem Cell Migration +21

Tumoral RANKL activates astrocytes that promote glioma cell invasion through cytokine signaling

Jun-Kyum Kim, Xiong Jin, Young-Woo Sohn, +12

Cancer Letters

Neuro-oncologyGliomaCytokine SignalingMedicineBrain-immune Interaction +9

The ID1-CULLIN3 Axis Regulates Intracellular SHH and WNT Signaling in Glioblastoma Stem Cells

Xun Jin, Hye-Min Jeon, Xiong Jin, +13

Cell Reports

Wnt SignalingCancer BiologyGliomaTumor BiologyTranscriptional Regulation +19

Irradiation induces glioblastoma cell senescence and senescence-associated secretory phenotype

Hee-Young Jeon, Jun-Kyum Kim, Seok Won Ham, +6

Tumor Biology

Human telomerase catalytic subunit (hTERT) suppresses p53-mediated anti-apoptotic response via induction of basic fibroblast growth factor

Xun Jin, Samuel J. Beck, Young-Woo Sohn, +7

Experimental & Molecular Medicine

Tumor BiologyOncogenic AgentMedicineTelomerase ActivityApoptosis +13

hMSC-mediated Concurrent Delivery of Endostatin and Carboxylesterase to Mouse Xenografts Suppresses Glioma Initiation and Recurrence

Jinlong Yin, Jun-Kyum Kim, Jai-Hee Moon, +9

Molecular Therapy

Vascular NicheBiomedical EngineeringCancer BiologyGliomaTumor Biology +16

Ly6G+ inflammatory cells enable the conversion of cancer cells to cancer stem cells in an irradiated glioblastoma model

Hee-Young Jeon, Seok Won Ham, Jun-Kyum Kim, +10

Cell Death and Differentiation

Rab3a promotes brain tumor initiation and progression

Jun-Kyum Kim, Seung-Yup Lee, Chang-Won Park, +7

Molecular Biology Reports

Neuro-oncologyGliomaMedicineBrain Tumor InitiationTumor Suppressor +4

Inhibition of ID1–BMPR2 Intrinsic Signaling Sensitizes Glioma Stem Cells to Differentiation Therapy

Xiong Jin, Xun Jin, Leo J.Y. Kim, +8

Clinical Cancer Research