Robert C. M. Knaap

Middle East Respiratory Coronavirus Accessory Protein 4a Inhibits PKR-Mediated Antiviral Stress Responses

Huib H. Rabouw, Martijn A. Langereis, Robert C. M. Knaap et al. · PLoS Pathogens · 2016 · 193 citations · Full text

Immunology, Viral Pathogenesis, Innate Immunity +16

Crystal Structure of the Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Papain-like Protease Bound to Ubiquitin Facilitates Targeted Disruption of Deubiquitinating Activity to Demonstrate Its Role in Innate Immune Suppression

Ben A. Bailey-Elkin, Robert C. M. Knaap, Garrett Johnson et al. · Journal of Biological Chemistry · 2014 · 160 citations · Full text

Potent and selective inhibition of pathogenic viruses by engineered ubiquitin variants

Wei Zhang, Ben A. Bailey-Elkin, Robert C. M. Knaap et al. · PLoS Pathogens · 2017 · 59 citations · Full text

Viral Replication, Synthetic Virology, Immunology +19

Deubiquitinating activity of SARS-CoV-2 papain-like protease does not influence virus replication or innate immune responses in vivo

Mariska van Huizen, Jonna R. Bloeme - ter Horst, Heidi L. M. De Gruyter et al. · PLoS Pathogens · 2024 · 19 citations · Full text

Profiling DUBs and Ubl-specific proteases with activity-based probes

Paul P. Geurink, Gerbrand J. van der Heden van Noort, Monique P. C. Mulder et al. · Methods in enzymology on CD-ROM/Methods in enzymology · 2019 · 17 citations

Natural Sciences, Medicine, Computational Biology +7