Michael S. Perkinton

Phosphatidylinositol 3‐kinase is a central mediator of NMDA receptor signalling to MAP kinase (Erk1/2), Akt/PKB and CREB in striatal neurones

Michael S. Perkinton, James E. Ip, Gemma L. Wood et al. · Journal of Neurochemistry · 2002 · 209 citations

Life Sciences, Cell Biology, Neurobiology +16

Ca²⁺-Permeable AMPA Receptors Induce Phosphorylation of cAMP Response Element-Binding Protein through a Phosphatidylinositol 3-Kinase-Dependent Stimulation of the Mitogen-Activated Protein Kinase Signaling Cascade in Neurons

Michael S. Perkinton, Talvinder S. Sihra, Robert J. Williams · Journal of Neuroscience · 1999 · 197 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Extracellular Monomeric and Aggregated Tau Efficiently Enter Human Neurons through Overlapping but Distinct Pathways

Lewis Evans, Thomas Wassmer, Graham Fraser et al. · Cell Reports · 2018 · 194 citations · Full text

Life Sciences, Molecular Biology, Neuroscience +14

Synaptic NMDA Receptor Activation Stimulates α-Secretase Amyloid Precursor Protein Processing and Inhibits Amyloid-β Production

Sarah E. Hoey, Robert J. Williams, Michael S. Perkinton · Journal of Neuroscience · 2009 · 175 citations · Full text

Life Sciences, Neurobiology, Neuroscience +13

PrP is a central player in toxicity mediated by soluble aggregates of neurodegeneration-causing proteins

Grant T. Corbett, Zemin Wang, Wei Hong et al. · Acta Neuropathologica · 2019 · 161 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17