Sunil Acharya

Targeting a cytokine checkpoint enhances the fitness of armored cord blood CAR-NK cells

May Daher, Rafet Başar, Elif Gokdemir et al. · Blood · 2020 · 272 citations · Full text

Targeting the αv integrin/TGF-β axis improves natural killer cell function against glioblastoma stem cells

Hila Shaim, Mayra Shanley, Rafet Başar et al. · Journal of Clinical Investigation · 2021 · 234 citations · Full text

Cell Therapy, Immunology, Immune Regulation +28

14-3-3ζ Turns TGF-β’s Function from Tumor Suppressor to Metastasis Promoter in Breast Cancer by Contextual Changes of Smad Partners from p53 to Gli2

Jia Xu, Sunil Acharya, Özgür Şahin et al. · Cancer Cell · 2015 · 180 citations · Full text

Smad Partners, Medicine, Cancer Cell Biology +9

KIR-based inhibitory CARs overcome CAR-NK cell trogocytosis-mediated fratricide and tumor escape

Ye Li, Rafet Başar, Guohui Wang et al. · Nature Medicine · 2022 · 152 citations · Full text

Natural Killer Cells, Immunology, Tumor Escape +10

Loss of metabolic fitness drives tumor resistance after CAR-NK cell therapy and can be overcome by cytokine engineering

Li Li, Vakul Mohanty, Jinzhuang Dou et al. · Science Advances · 2023 · 94 citations · Full text

Immunology, Nk Cells, Car-nk Cell Therapy +18