Genomic atlas of the plasma metabolome prioritizes metabolites implicated in human diseases

Yiheng Chen, Tianyuan Lu, U. Pettersson, +16

Nature Genetics

Metabolic NetworkBiochemistryHuman DiseasesMedicineGenetic Epidemiology +10

Proteome-wide Mendelian randomization implicates nephronectin as an actionable mediator of the effect of obesity on COVID-19 severity

Satoshi Yoshiji, Guillaume Butler‐Laporte, Tianyuan Lu, +27

Nature Metabolism

ObesityMetabolic SyndromeMetabolic DisorderMedicineObesity Management +5

Bullous pemphigoid associated with dipeptidyl peptidase‐4 inhibitors: A report of five cases

Satoshi Yoshiji, Takaaki Murakami, Shin‐ichi Harashima, +6

Journal of Diabetes Investigation

Autoimmune DiseaseAllergyMedicineJapanese CasesPathology +13

HLA allele-calling using multi-ancestry whole-exome sequencing from the UK Biobank identifies 129 novel associations in 11 autoimmune diseases

Guillaume Butler‐Laporte, Tomoko Nakanishi, Tianyuan Lu, +18

Communications Biology

Dose-dependent Association of Alcohol Consumption With Obesity and Type 2 Diabetes: Mendelian Randomization Analyses

Tianyuan Lu, Tomoko Nakanishi, Satoshi Yoshiji, +3

The Journal of Clinical Endocrinology & Metabolism

First Japanese Family With <i>PDX1</i>-MODY (MODY4): A Novel <i>PDX1</i> Frameshift Mutation, Clinical Characteristics, and Implications

Satoshi Yoshiji, Yukio Horikawa, Sodai Kubota, +9

Journal of the Endocrine Society

Increasing serum iron levels and their role in the risk of infectious diseases: a Mendelian randomization approach

Guillaume Butler‐Laporte, Yossi Farjoun, Yiheng Chen, +7

International Journal of Epidemiology

Integrative proteogenomic analysis identifies COL6A3-derived endotrophin as a mediator of the effect of obesity on coronary artery disease

Satoshi Yoshiji, Tianyuan Lu, Guillaume Butler‐Laporte, +26

Nature Genetics

Dehydration is associated with production of organic osmolytes and predicts physical long-term symptoms after COVID-19: a multicenter cohort study

Michael Hultström, Miklós Lipcsey, Tomoko Nakanishi, +13

Critical Care

Circulating Metabolite Abundances Associated With Risks of Bipolar Disorder, Schizophrenia, and Depression: A Mendelian Randomization Study

Tianyuan Lu, Yiheng Chen, Satoshi Yoshiji, +4

Biological Psychiatry