Birgit Dreier

Toward controlling gene expression at will: Specific regulation of the <i>erbB</i> - <i>2</i> / <i>HER</i> - <i>2</i> promoter by using polydactyl zinc finger proteins constructed from modular building blocks

Roger R. Beerli, David J. Segal, Birgit Dreier et al. · Proceedings of the National Academy of Sciences · 1998 · 538 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

Toward controlling gene expression at will: Selection and design of zinc finger domains recognizing each of the 5′-GNN-3′ DNA target sequences

David J. Segal, Birgit Dreier, Roger R. Beerli et al. · Proceedings of the National Academy of Sciences · 1999 · 423 citations

Life Sciences, Biology, Molecular Biology +17

Positive and negative regulation of endogenous genes by designed transcription factors

Roger R. Beerli, Birgit Dreier, Carlos F. Barbas · Proceedings of the National Academy of Sciences · 2000 · 348 citations

Life Sciences, Cancer Biology, Molecular Biology +17

Development of Zinc Finger Domains for Recognition of the 5′-ANN-3′ Family of DNA Sequences and Their Use in the Construction of Artificial Transcription Factors

Birgit Dreier, Roger R. Beerli, David J. Segal et al. · Journal of Biological Chemistry · 2001 · 330 citations · Full text

Life Sciences, Biology, Molecular Biology +14

Efficient Tumor Targeting with High-Affinity Designed Ankyrin Repeat Proteins: Effects of Affinity and Molecular Size

Christian Zahnd, Martin Kawe, Michael T. Stumpp et al. · Cancer Research · 2010 · 246 citations

Medicine, Molecular Biology, Oncology +17