Genome-scale analysis of metazoan replication origins reveals their organization in specific but flexible sites defined by conserved features

Christelle Cayrou, Philippe Coulombe, Alice Vigneron, +8

Genome Research

The chromatin environment shapes DNA replication origin organization and defines origin classes

Christelle Cayrou, Benoît Ballester, Isabelle Peiffer, +5

Genome Research

ChromatinChromatin StructureChromatin RemodelingChromatin MarksNatural Sciences +13

Involvement of G-quadruplex regions in mammalian replication origin activity

Paulina Prorok, Marie Artufel, Antoine Aze, +11

Nature Communications

New insights into replication origin characteristics in metazoans

Christelle Cayrou, Philippe Coulombe, Aurore Puy, +4

Cell Cycle

GeneticsGenomic MechanismMolecular GeneticsGenomicsMetazoan Cell Lines +14

Rho Family GTPases Are Required for Activation of Jak/STAT Signaling by G Protein-Coupled Receptors

S. William Pelletier, François Duhamel, Philippe Coulombe, +2

Molecular and Cellular Biology

Rapid Turnover of Extracellular Signal-Regulated Kinase 3 by the Ubiquitin-Proteasome Pathway Defines a Novel Paradigm of Mitogen-Activated Protein Kinase Regulation during Cellular Differentiation

Philippe Coulombe, Geneviève Rodier, S. William Pelletier, +2

Molecular and Cellular Biology

Unstable ProteinCytoskeletonErk3 Kinase DomainSignaling PathwayCell Regulation +19

N-Terminal Ubiquitination of Extracellular Signal-Regulated Kinase 3 and p21 Directs Their Degradation by the Proteasome

Philippe Coulombe, Geneviève Rodier, Éric Bonneil, +2

Molecular and Cellular Biology

Differential Regulation of P27Kip1 Expression by Mitogenic and Hypertrophic Factors

Marc J. Servant, Philippe Coulombe, Benjamin Turgeon, +1

The Journal of Cell Biology

Phosphorylation of Skp2 regulated by CDK2 and Cdc14B protects it from degradation by APCCdh1 in G1 phase

Geneviève Rodier, Philippe Coulombe, Pierre‐Luc Tanguay, +2

The EMBO Journal

Signal TransductionCell RegulationCell DivisionG1 PhaseMolecular Pathway +7

Involvement of the IκB Kinase (IKK)-Related Kinases Tank-Binding Kinase 1/IKKi and Cullin-Based Ubiquitin Ligases in IFN Regulatory Factor-3 Degradation

Annie Bibeau-Poirier, Simon‐Pierre Gravel, Jean-François Clément, +7

The Journal of Immunology