Saturated Fatty Acid and TLR Signaling Link β Cell Dysfunction and Islet Inflammation

Kosei Eguchi, Ichiro Manabe, Yumiko Tanaka, +11

Cell Metabolism

InflammationMetabolic SyndromeInsulin SignalingPhysiologyImmunology +10

Decrease in Membrane Phospholipid Unsaturation Induces Unfolded Protein Response

Hiroyuki Ariyama, Nozomu Kono, Shinji Matsuda, +2

Journal of Biological Chemistry

Autophagosome formation is initiated at phosphatidylinositol synthase‐enriched <scp>ER</scp> subdomains

Taki Nishimura, Norito Tamura, Nozomu Kono, +4

The EMBO Journal

Cell AutophagyAutophagyAutophagosome FormationLipophagyCellular Biochemistry +3

Structure of SARS-CoV-2 membrane protein essential for virus assembly

Zhikuan Zhang, Norimichi Nomura, Yukiko Muramoto, +11

Nature Communications

LPIAT1 regulates arachidonic acid content in phosphatidylinositol and is required for cortical lamination in mice

Hyeon‐Cheol Lee, Takao Inoué, Junko Sasaki, +13

Molecular Biology of the Cell

Brain DevelopmentGeneticsCellular PhysiologyCortical LaminationPi Phosphates +18

<i>Caenorhabditis elegans mboa-7</i>, a Member of the MBOAT Family, Is Required for Selective Incorporation of Polyunsaturated Fatty Acids into Phosphatidylinositol

Hyeon‐Cheol Lee, Takao Inoue, Rieko Imae, +6

Molecular Biology of the Cell

Mboa-7 MutantsSelective IncorporationNutrient SignallingFatty AcidsMboat Family +15

Impaired α-TTP-PIPs Interaction Underlies Familial Vitamin E Deficiency

Nozomu Kono, Umeharu Ohto, Tatsufumi Hiramatsu, +4

Science

Proteinlipid InteractionMolecular RegulationArginine MutantsGeneticsGenetic Epidemiology +17

LPIAT1/MBOAT7 depletion increases triglyceride synthesis fueled by high phosphatidylinositol turnover

Yuki Tanaka, Yuta Shimanaka, Andrea Caddeo, +14

Gut

Identification of genes and pathways involved in the synthesis of Mead acid (20:3n − 9), an indicator of essential fatty acid deficiency

Ikuyo Ichi, Nozomu Kono, Yuka Arita, +6

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

BiologyBiosynthesisBiochemistryLipid NutritionMead Acid +3

Membrane lipid saturation activates <scp>IRE</scp>1α without inducing clustering

Yuto Kitai, Hiroyuki Ariyama, Nozomu Kono, +3

Genes to Cells