Pauline J. van der Watt

The Karyopherin proteins, Crm1 and Karyopherin β1, are overexpressed in cervical cancer and are critical for cancer cell survival and proliferation

Pauline J. van der Watt, Christopher Maske, Denver T. Hendricks et al. · International Journal of Cancer · 2008 · 247 citations · Full text

Karyopherin β1, Pathology, Cell Death +16

Targeting the Nuclear Import Receptor Kpnβ1 as an Anticancer Therapeutic

Pauline J. van der Watt, Alicia Chi, Tamara Stelma et al. · Molecular Cancer Therapeutics · 2016 · 80 citations · Full text

Overexpression of Kpnβ1 and Kpnα2 Importin Proteins in Cancer Derives from Deregulated E2F Activity

Pauline J. van der Watt, Ellen Ngarande, Virna D. Leaner · PLoS ONE · 2011 · 48 citations · Full text

The nuclear exporter, Crm1, is regulated by NFY and Sp1 in cancer cells and repressed by p53 in response to DNA damage

Pauline J. van der Watt, Virna D. Leaner · Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms · 2011 · 46 citations

Genome Instability, Systems Biology, Dna Damage +10

Photolon™, a chlorin e6 derivative, triggers ROS production and light-dependent cell death via necrosis

Louise Copley, Pauline J. van der Watt, K.W.A. Wirtz et al. · The International Journal of Biochemistry & Cell Biology · 2007 · 45 citations · Full text

Triggers Ros Production, Biochemistry, Photochemistry +15