Transcriptional and posttranslational up-regulation of HER3 (ErbB3) compensates for inhibition of the HER2 tyrosine kinase

Joan T. Garrett, Maria G. Olivares, Cammie Rinehart, +10

Proceedings of the National Academy of Sciences

Pi3k PathwayTumor BiologyTranscriptional RegulationSignaling PathwayCell Regulation +18

Loss of Phosphatase and Tensin Homolog or Phosphoinositol-3 Kinase Activation and Response to Trastuzumab or Lapatinib in Human Epidermal Growth Factor Receptor 2–Overexpressing Locally Advanced Breast Cancers

Bhuvanesh Dave, Ilenia Migliaccio, Maya Gutierrez, +12

Journal of Clinical Oncology

Three-Dimensional In Vitro Co-Culture Model of Breast Tumor using Magnetic Levitation

Hamsa Jaganathan, Jacob A. Gage, Fransisca Leonard, +4

Scientific Reports

Inhibition of iNOS as a novel effective targeted therapy against triple-negative breast cancer

Sergio Granados‐Principal, Yi Liu, María L. Guevara, +12

Breast Cancer Research

Drug-repositioning screening identified piperlongumine as a direct STAT3 inhibitor with potent activity against breast cancer

Uddalak Bharadwaj, T. Kris Eckols, Mikhail Kolosov, +13

Oncogene

Direct Stat3 InhibitorMedicineBreast CancerPharmacotherapyIdentified Piperlongumine +6

Modulation of the Hepatitis C Virus RNA-dependent RNA Polymerase Activity by the Non-Structural (NS) 3 Helicase and the NS4B Membrane Protein

S. Piccininni, Agoritsa Varaklioti, Maria Nardelli, +3

Journal of Biological Chemistry

Virus StructureViral ReplicationNs4b Membrane ProteinBiochemistryHepatitis C Virus +13

Phosphoproteomic mass spectrometry profiling links Src family kinases to escape from HER2 tyrosine kinase inhibition

Brent N. Rexer, Amy‐Joan L. Ham, Cammie Rinehart, +8

Oncogene

Links Src FamilySignal TransductionSignaling PathwayBiochemistryMedicine +12

Trastuzumab-Resistant Cells Rely on a HER2-PI3K-FoxO-Survivin Axis and Are Sensitive to PI3K Inhibitors

Anindita Chakrabarty, Neil E. Bhola, Cammie R. Sutton, +5

Cancer Research

Targeting RPL39 and MLF2 reduces tumor initiation and metastasis in breast cancer by inhibiting nitric oxide synthase signaling

Bhuvanesh Dave, Sergio Granados‐Principal, Rui Zhu, +20

Proceedings of the National Academy of Sciences

Chloroquine Eliminates Cancer Stem Cells Through Deregulation of Jak2 and DNMT1

Dong Soon Choi, Elvin Blanco, Yoo-Shin Kim, +14

Stem Cells