Raloxifene (LY139481 HCI) prevents bone loss and reduces serum cholesterol without causing uterine hypertrophy in ovariectomized rats.

Larry J. Black, Masahiko Sato, Ellen R. Rowley, +7

Journal of Clinical Investigation

Lipid PeroxidationGynecologyPharmacotherapyOsteoporosisOxidative Stress +18

Structure−Activity Relationships of Selective Estrogen Receptor Modulators:  Modifications to the 2-Arylbenzothiophene Core of Raloxifene

Timothy A. Grese, Stephen Cho, Don R. Finley, +15

Journal of Medicinal Chemistry

GynecologyRaloxifene AnalogsPharmacotherapyChemical BiologyPharmaceutical Chemistry +21

Environmental estrogens: Effects on cholesterol lowering and bone in the ovariectomized rat

Jeffrey A. Dodge, Andrew L. Glasebrook, David E. Magee, +4

The Journal of Steroid Biochemistry and Molecular Biology

Ovariectomized RatPhysiologyGynecologyFemale Reproductive FunctionEnvironmental Estrogens +10

Synthesis and Pharmacology of Conformationally Restricted Raloxifene Analogues:  Highly Potent Selective Estrogen Receptor Modulators

Timothy A. Grese, Lewis D. Pennington, James P. Sluka, +13

Journal of Medicinal Chemistry

Dual-energy X-ray absorptiometry of raloxifene effects on the lumbar vertebrae and femora of ovariectomized rats

Masahiko Sato, Cindy McClintock, John Kim, +4

Journal of Bone and Mineral Research

The effects of raloxifene on tibia histomorphometry in ovariectomized rats.

Glenda L. Evans, David E. Magee, Masahiko Sato, +1

Endocrinology

Raloxifene is a Tissue‐Selective Agonist/Antagonist That Functions through the Estrogen Receptor

Robin Fuchs‐Young, A. L. GLASEBROOK, Lorri L. Short, +6

Annals of the New York Academy of Sciences

Molecular PharmacologyMedicineHormonal ReceptorEstrogen ReceptorMechanism Of Action +7

Raloxifene inhibits bone turnover and prevents further cancellous bone loss in adult ovariectomized rats with established osteopenia.

Glenda L. Evans, H.U. Bryant, David E. Magee, +1

Endocrinology

Hormonal ContraceptiveBone RepairGynecologyOsteoporosisOrthopaedic Surgery +18

Effect of weight manipulation on bone loss due to ovariectomy and the protective effects of estrogen in the rat

Roger E. Roudebush, David E. Magee, D. N. Benslay, +2

Calcified Tissue International

Bone LossBone HealthBody CompositionMedicinePhysiology +10

Clomiphene Prevents Cancellous Bone Loss from Tibia of Ovariectomized Rats

Maritza A. Jimenez, David E. Magee, H.U. Bryant, +1

Endocrinology