Autophagy negatively regulates Wnt signalling by promoting Dishevelled degradation

Chan Gao, Weipeng Cao, Lan Bao, +8

Nature Cell Biology

Cell AutophagyMitophagySignal TransductionSignaling PathwayAutophagy +4

Characterization of the Transcriptome of Nascent Hair Cells and Identification of Direct Targets of the Atoh1 Transcription Factor

Tiantian Cai, Hsin‐I Jen, Hyojin Kang, +3

Journal of Neuroscience

GeneticsNascent Hair CellsGene CharacterizationGene Regulatory NetworkTranscription Factor Atoh1 +17

Cellular reprogramming with ATOH1, GFI1, and POU4F3 implicate epigenetic changes and cell-cell signaling as obstacles to hair cell regeneration in mature mammals

Amrita A. Iyer, Ishwar Hosamani, John D. Nguyen, +13

eLife

Hair CellsHair CellLineage PlasticityDevelopmental BiologyCell Lineage +12

Saikosaponin a inhibits the proliferation and activation of T cells through cell cycle arrest and induction of apoptosis

Yang Sun, Tiantian Cai, Xiaobin Zhou, +1

International Immunopharmacology

InflammationCytokineSignal TransductionSignaling PathwayMedicine +10

Lineage tracing of Sox2-expressing progenitor cells in the mouse inner ear reveals a broad contribution to non-sensory tissues and insights into the origin of the organ of Corti

Rende Gu, Rogers M. Brown, Chih‐Wei Hsu, +6

Developmental Biology

Cell LineageDevelopmental BiologyMouse Inner EarMorphogenesisNeuroscience +9

Transcriptomic Analysis of Mouse Cochlear Supporting Cell Maturation Reveals Large-Scale Changes in Notch Responsiveness Prior to the Onset of Hearing

Juan C. Maass, Rende Gu, Tiantian Cai, +8

PLoS ONE

Notch BlockadeCell SpecializationTranscriptional RegulationAuditory ScienceFunctional Maturation +21

Origin of the Reflectin Gene and Hierarchical Assembly of Its Protein

Zhe Guan, Tiantian Cai, Zhongmin Liu, +21

Current Biology

Protein FunctionBiochemistryProtein AssemblyProtein FoldingNatural Sciences +9

Dissection of the role of paeoniflorin in the traditional Chinese medicinal formula Si-Ni-San against contact dermatitis in mice

Yang Sun, Yi Dong, Huijuan Jiang, +5

Life Sciences

MedicineContact DermatitisSkin AllergyTopical DrugDermatology +4

Preparation and Characterization of Antioxidant Peptides from Carrot Seed Protein

Nanhui Ye, Pei Hu, Shuli Xu, +5

Journal of Food Quality

Food ChemistryCarrot SeedPolyphenolicsFood Bioactive CompoundBiochemistry +12

The Role of Atonal Factors in Mechanosensory Cell Specification and Function

Tiantian Cai, Andrew K. Groves

Molecular Neurobiology

EngineeringCytoskeletonMechanotransductionCellular PhysiologyAtonal Factors +14