Rutger W.H.M. Staffhorst

Nanocapsules: lipid-coated aggregates of cisplatin with high cytotoxicity

Koert N.J. Burger, Rutger W.H.M. Staffhorst, H.C. de Vijlder et al. · Nature Medicine · 2002 · 189 citations · Full text

Pharmacy, Pharmaceutics, Pharmacology +14

Transport Studies of Doxorubicin in Model Membranes Indicate a Difference in Passive Diffusion across and Binding at the Outer and Inner Leaflet of the Plasma Membrane

Gea Speelmans, Rutger W.H.M. Staffhorst, Ben de Kruijff et al. · Biochemistry · 1994 · 114 citations

Life Sciences, Biochemistry, Biophysics +17

The interaction of the anti-cancer drug cisplatin with phospholipids is specific for negatively charged phospholipids and takes place at low chloride ion concentration

Gea Speelmans, Wendy H.H.M. Sips, R.J.H. Grisel et al. · Biochimica et Biophysica Acta (BBA) - Biomembranes · 1996 · 70 citations

Medicine, Oncology, Pharmacology +14

Cisplatin Complexes with Phosphatidylserine in Membranes

Gea Speelmans, Rutger W.H.M. Staffhorst, Kees Versluis et al. · Biochemistry · 1997 · 68 citations

Life Sciences, Biochemistry, Pharmacology +11

Self-Reproduction of Fatty Acid Vesicles: A Combined Experimental and Simulation Study

Albert J. Markvoort, N. Pfleger, Rutger W.H.M. Staffhorst et al. · Biophysical Journal · 2010 · 58 citations · Full text

Natural Sciences, Biochemistry, Biophysics +14