Concepedia

Carleigh A. O’Brien

CA

Statistics

Publications

10

Citations

459

H-Index

10

Active since

2017

Affiliations

University of Virginia(Current)

University of Pennsylvania

Children's Hospital of Philadelphia

University of California, Irvine

Vrije Universiteit Brussel

Carleigh A. O’Brien is an author at University of Virginia specializing in life sciences, neuroimmunology, and neuroinflammation.

ORCID

Publications per year

2017–2025

10

Publications

10

Gasdermin-D-dependent IL-1α release from microglia promotes protective immunity during chronic Toxoplasma gondii infection

Samantha J. Batista, Katherine M. Still, David M. Johanson et al. · Nature Communications · 2020 · 113 citations · Full text

, , +17

Engineering an inhibitor-resistant human CSF1R variant for microglia replacement

Jean Paul Chadarevian, Sonia I Lombroso, Graham C. Peet et al. · The Journal of Experimental Medicine · 2022 · 93 citations · Full text

, , +10

Monocytes can efficiently replace all brain macrophages and fetal liver monocytes can generate bona fide SALL1+ microglia

Jonathan Bastos, Carleigh A. O’Brien, Mónica Vara‐Pérez et al. · Immunity · 2025 · 52 citations · Full text

, , +15

Astrocytes promote a protective immune response to brain Toxoplasma gondii infection via IL-33-ST2 signaling

Katherine M. Still, Samantha J. Batista, Carleigh A. O’Brien et al. · PLoS Pathogens · 2020 · 46 citations · Full text

, , +17

Microglia are not necessary for maintenance of blood-brain barrier properties in health, but PLX5622 alters brain endothelial cholesterol metabolism

Caterina P. Profaci, Sean Harvey, Kaja Bajc et al. · Neuron · 2024 · 45 citations · Full text

, , +14

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