Katsumi Koike

Morphine, Oxycodone, and Fentanyl Exhibit Different Analgesic Profiles in Mouse Pain Models

Kazuhisa Minami, Minoru Hasegawa, Hisanori Ito et al. · Journal of Pharmacological Sciences · 2009 · 62 citations · Full text

Medicine, Anesthesiology, Pharmacology +13

2-Arylimino-5,6-dihydro-4H-1,3-thiazines as a new class of cannabinoid receptor agonists. Part 2: Orally bioavailable compounds

Hiroyuki Kai, Yasuhide Morioka, Minoru Tomida et al. · Bioorganic & Medicinal Chemistry Letters · 2007 · 36 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +9

2-Arylimino-5,6-dihydro-4H-1,3-thiazines as a new class of cannabinoid receptor agonists. Part 3: Synthesis and activity of isosteric analogs

Hiroyuki Kai, Yasuhide Morioka, Yuji Koriyama et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 36 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +9

Pharmacologic effects of naldemedine, a peripherally acting μ‐opioid receptor antagonist, in in vitro and in vivo models of opioid‐induced constipation

Toshiyuki Kanemasa, Katsumi Koike, Tohko Arai et al. · Neurogastroenterology & Motility · 2019 · 36 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +17

Distinct Relations Among Plasma Concentrations Required for Different Pharmacological Effects in Oxycodone, Morphine, and Fentanyl

Atsushi Nakamura, Minoru Hasegawa, Hisanori Ito et al. · Journal of Pain & Palliative Care Pharmacotherapy · 2011 · 35 citations

Medicine, Pharmacokinetics, Pharmacology +17