Concepedia
5
Publications
135
Citations
H-Index
2019
Active since
Affiliations
Charles University(Current)
Czech Academy of Sciences, Institute of Organic Chemistry and Biochemistry
University of Chemistry and Technology, Prague
Zdeněk Vavřina is an author at Charles University.
Publications per year
2019–2023
Enzymatic Preparation of 2′–5′,3′–5′-Cyclic Dinucleotides, Their Binding Properties to Stimulator of Interferon Genes Adaptor Protein, and Structure/Activity Correlations
Barbora Novotná, Lenka Vaneková, Martin Zavřel et al. · Journal of Medicinal Chemistry · 2019 · 59 citations · Full text
Design, Synthesis, and Biochemical and Biological Evaluation of Novel 7-Deazapurine Cyclic Dinucleotide Analogues as STING Receptor Agonists
Zdeněk Vavřina, Pavla Perlíková, Nemanja Milisavljevič et al. · Journal of Medicinal Chemistry · 2022 · 23 citations · Full text
Protein–Ligand Interactions in the STING Binding Site Probed by Rationally Designed Single-Point Mutations: Experiment and Theory
Zdeněk Vavřina, Ondrej Gutten, Miroslav Smola et al. · Biochemistry · 2021 · 22 citations
Synthetic Stimulator of Interferon Genes (STING) Agonists Induce a Cytokine-Mediated Anti-Hepatitis B Virus Response in Nonparenchymal Liver Cells
Markéta Pimková Polidarová, Lenka Vaneková, Petra Břehová et al. · ACS Infectious Diseases · 2022 · 20 citations
Vinylphosphonate-based cyclic dinucleotides enhance STING-mediated cancer immunotherapy
Milan Dejmek, Andrea Brázdová, Tomáš Otava et al. · European Journal of Medicinal Chemistry · 2023 · 11 citations · Full text
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