Heng Ru

Structural Analysis of the STING Adaptor Protein Reveals a Hydrophobic Dimer Interface and Mode of Cyclic di-GMP Binding

Songying Ouyang, Xianqiang Song, Yaya Wang et al. · Immunity · 2012 · 325 citations · Full text

Protein Chemistry, Sting Adaptor Protein, Proteinlipid Interaction +11

AARS1 and AARS2 sense l-lactate to regulate cGAS as global lysine lactyltransferases

Heyu Li, Chao Liu, Ran Li et al. · Nature · 2024 · 223 citations

Signal Transduction, Biochemistry, Natural Sciences +8

Molecular Mechanism of V(D)J Recombination from Synaptic RAG1-RAG2 Complex Structures

Heng Ru, Melissa G. Chambers, Tian‐Min Fu et al. · Cell · 2015 · 185 citations · Full text

Signal Transduction, Molecular Mechanism, Molecular Biology +4

Characterization of T and B cell repertoire diversity in patients with RAG deficiency

Yu Nee Lee, Francesco Frugoni, Kerry Dobbs et al. · Science Immunology · 2016 · 109 citations · Full text

Structural analysis of asparaginyl endopeptidase reveals the activation mechanism and a reversible intermediate maturation stage

Lixia Zhao, Tian Hua, Christopher Crowley et al. · Cell Research · 2014 · 99 citations · Full text

Protein Secretion, Protein Function, Protein Assembly +11