Matthew Gosden

Tissue-specific CTCF–cohesin-mediated chromatin architecture delimits enhancer interactions and function in vivo

Lars L. P. Hanssen, Mira Kassouf, A. Marieke Oudelaar et al. · Nature Cell Biology · 2017 · 233 citations · Full text

Chromatin, Transcriptional Regulation, Chromatin Structure +11

DeepC: predicting 3D genome folding using megabase-scale transfer learning

Ron Schweßinger, Matthew Gosden, Damien J. Downes et al. · Nature Methods · 2020 · 216 citations · Full text

Long-read Sequencing, Engineering, Computational Genomics +7

Dynamics of the 4D genome during in vivo lineage specification and differentiation

A. Marieke Oudelaar, Robert A. Beagrie, Matthew Gosden et al. · Nature Communications · 2020 · 122 citations · Full text

Editing an α-globin enhancer in primary human hematopoietic stem cells as a treatment for β-thalassemia

Sachith Mettananda, Chris Fisher, Deborah Hay et al. · Nature Communications · 2017 · 101 citations · Full text

Analysis of Differentiation Protocols Defines a Common Pancreatic Progenitor Molecular Signature and Guides Refinement of Endocrine Differentiation

Agata Wesolowska‐Andersen, Rikke Rejnholdt Jensen, Marta Perez‐Alcantara et al. · Stem Cell Reports · 2019 · 56 citations · Full text

Genetics, Molecular Genetics, Cell Specialization +19