Jason Karpac

PGRP-SC2 Promotes Gut Immune Homeostasis to Limit Commensal Dysbiosis and Extend Lifespan

Linlin Guo, Jason Karpac, Susan L. Tran et al. · Cell · 2014 · 464 citations · Full text

Inflammation, Chronic Inflammatory Diseases, Dysbiosis +13

Mitochondrial ROS promotes susceptibility to infection via gasdermin D-mediated necroptosis

Chi G. Weindel, E. Martínez, Xiao Zhao et al. · Cell · 2022 · 349 citations · Full text

Inflammation, Mitophagy, Mitochondrial Function +8

Lifespan Extension by Preserving Proliferative Homeostasis in Drosophila

Benoît Biteau, Jason Karpac, Stephen Supoyo et al. · PLoS Genetics · 2010 · 344 citations · Full text

Anti-aging, Proliferative Homeostasis, Biogerontology +17

Muscle Directs Diurnal Energy Homeostasis through a Myokine-Dependent Hormone Module in Drosophila

Xiao Zhao, Jason Karpac · Current Biology · 2017 · 104 citations · Full text

Biology, Energy Homeostasis, Signal Transduction +8

Notch-Mediated Suppression of TSC2 Expression Regulates Cell Differentiation in the Drosophila Intestinal Stem Cell Lineage

Subir Kapuria, Jason Karpac, Benoît Biteau et al. · PLoS Genetics · 2012 · 100 citations · Full text

Posterior Midgut, Stem Cell Biology, Cell Specialization +17