ATF-2 is preferentially activated by stress-activated protein kinases to mediate c-jun induction in response to genotoxic agents.

Hans van Dam, Dagmar Wilhelm, Ingrid Herr, +3

The EMBO Journal

Transcriptional RegulationSignal TransductionSignaling PathwayCell RegulationApoptosis +6

Heterodimer formation of cJun and ATF-2 is responsible for induction of c-jun by the 243 amino acid adenovirus E1A protein.

Hans van Dam, Monique C.A. Duyndam, Robbert J. Rottier, +6

The EMBO Journal

Molecular PhysiologySignal TransductionHeterodimer FormationMolecular VirologyPathogenesis +7

Site-Specific Identification of SUMO-2 Targets in Cells Reveals an Inverted SUMOylation Motif and a Hydrophobic Cluster SUMOylation Motif

Ivan Matić, Joost Schimmel, Ivo A. Hendriks, +6

Molecular Cell

Protein FunctionSignal TransductionProtein ExpressionMolecular PathwayMedicine +9

OTUB2 Promotes Cancer Metastasis via Hippo-Independent Activation of YAP and TAZ

Zhengkui Zhang, Jinjin Du, Shuai Wang, +15

Molecular Cell

Signaling PathwayCell SignalingMedicineHippo-independent ActivationCell Biology +5

The TGF-β/Smad pathway induces breast cancer cell invasion through the up-regulation of matrix metalloproteinase 2 and 9 in a spheroid invasion model system

Eliza Wiercinska, Hildegonda P. H. Naber, Evangelia Pardali, +3

Breast Cancer Research and Treatment

Breast OncologyMedicineCell-matrix InteractionCancer Cell InvasionBreast Cancer +9

YAP antagonizes innate antiviral immunity and is targeted for lysosomal degradation through IKKɛ-mediated phosphorylation

Shuai Wang, Feng Xie, Feng Chu, +11

Nature Immunology

Protein FunctionSignal TransductionViral ImmunityImmunologyAntiviral Response +9

Tumor-derived exosomes antagonize innate antiviral immunity

Liang Gao, Lin Wang, Tong Dai, +10

Nature Immunology

Tumor-derived ExosomesImmunologyTumor ImmunityAntiviral ResponseExtracellular Microvesicles +6

Inflammation induces endothelial‐to‐mesenchymal transition and promotes vascular calcification through downregulation of BMPR2

Gonzalo Sánchez‐Duffhues, Amaya García de Vinuesa, Vera van de Pol, +7

The Journal of Pathology

ImmunologyImmune RegulationPathologyCell DifferentiationTumor Biology +19

Characterization of cDNA for nodulin-75 of soybean: A gene product involved in early stages of root nodule development

Henk Franssen, Jan‐Peter Nap, Ton Gloudemans, +6

Proceedings of the National Academy of Sciences

Breast cancer metastasis suppressor OTUD1 deubiquitinates SMAD7

Zhengkui Zhang, Fan Yao, Feng Xie, +17

Nature Communications