Rapid Restoration of Cognition in Alzheimer's Transgenic Mice with 8-Hydroxy Quinoline Analogs Is Associated with Decreased Interstitial Aβ

Paul A. Adlard, Robert A. Cherny, David I. Finkelstein, +21

Neuron

Neurodegenerative DiseasesAlzheimer's DiseaseMolecular NeuroscienceMedicineSynaptic Transmission +13

The hypoxia imaging agent CuII(atsm) is neuroprotective and improves motor and cognitive functions in multiple animal models of Parkinson’s disease

Lin W. Hung, Victor L. Villemagne, Lesley Cheng, +24

The Journal of Experimental Medicine

Quantitative elemental bio-imaging of Mn, Fe, Cu and Zn in 6-hydroxydopamine induced Parkinsonism mouse models

Dominic J. Hare, Brian Reedy, Rudolf Grimm, +7

Metallomics

EngineeringTrace Element DistributionPet-mriQuantitative Elemental Bio-imagingNeurochemical Biomarkers +18

Insertion/Deletion Polymorphisms in the ΔNp63 Promoter Are a Risk Factor for Bladder Exstrophy Epispadias Complex

Simon Wilkins, Ke Wei Zhang, Istiak Mahfuz, +16

PLoS Genetics

GeneticsGenetic EpidemiologyHuman PolymorphismPathologyGene Characterization +23

Identification of novel mutations in the carbohydrate sulfotransferase gene (CHST6) causing macular corneal dystrophy.

Mohamed F. El-Ashry, Mai M. Abd El-Aziz, Simon Wilkins, +9

PubMed

The novel compound PBT434 prevents iron mediated neurodegeneration and alpha-synuclein toxicity in multiple models of Parkinson’s disease

David I. Finkelstein, Jessica L. Billings, Paul A. Adlard, +19

Acta Neuropathologica Communications

<i>Clostridioides difficile</i> infection damages colonic stem cells via TcdB, impairing epithelial repair and recovery from disease

Steven J. Mileto, Thierry Jardé, Kevin O. Childress, +15

Proceedings of the National Academy of Sciences

The role of preoperative CEA in the management of colorectal cancer: A cohort study from two cancer centres

Ali Riaz Baqar, Simon Wilkins, Margaret Staples, +3

International Journal of Surgery

Targeting the Progression of Parkinsons Disease

Jessica George, Samuel C. Mok, Daniel Moses, +4

Current Neuropharmacology

Three-dimensional elemental bio-imaging of Fe, Zn, Cu, Mn and P in a 6-hydroxydopamine lesioned mouse brain

Dominic J. Hare, Jessica George, Rudolph Grimm, +6

Metallomics

EngineeringThree-dimensional Elemental Bio-imagingToxicologyBrain InjuryNeurology +19