Direct Asymmetric <i>a</i><i>nti</i>-Mannich-Type Reactions Catalyzed by a Designed Amino Acid

Susumu Mitsumori, Haile Zhang, Paul Ha‐Yeon Cheong, +3

Journal of the American Chemical Society

Catalysis of 3-Pyrrolidinecarboxylic Acid and Related Pyrrolidine Derivatives in Enantioselective <i>anti</i>-Mannich-Type Reactions:  Importance of the 3-Acid Group on Pyrrolidine for Stereocontrol

Haile Zhang, Susumu Mitsumori, Naoto Utsumi, +8

Journal of the American Chemical Society

3-Acid GroupEngineeringRelated Pyrrolidine DerivativesAcid Group3-Pyrrolidinecarboxylic Acid +10

Dihydroxyacetone Variants in the Organocatalytic Construction of Carbohydrates:  Mimicking Tagatose and Fuculose Aldolases

Jeff T. Suri, Susumu Mitsumori, Klaus Albertshofer, +2

The Journal of Organic Chemistry

Bioorganic ChemistryEngineeringAldo-keto ReductaseGlycobiologyPolysaccharide +15

Synthesis and Biological Activity of Various Derivatives of a Novel Class of Potent, Selective, and Orally Active Prostaglandin D₂ Receptor Antagonists. 2. 6,6-Dimethylbicyclo[3.1.1]heptane Derivatives

Susumu Mitsumori, Tatsuo Tsuri, Tsunetoshi Honma, +10

Journal of Medicinal Chemistry

PharmacotherapyChemical BiologyVarious DerivativesPharmaceutical ChemistryChemical Derivative +19

Discovery of S-777469: An orally available CB2 agonist as an antipruritic agent

Masahide Odan, Natsuki Ishizuka, Yoshiharu Hiramatsu, +9

Bioorganic & Medicinal Chemistry Letters

Functional SelectivityMedicineAvailable Cb2 AgonistMechanism Of ActionPharmacotherapy +3

Total Synthesis of Terprenin, a Highly Potent and Novel Immunoglobulin E Antibody Suppressant

Kenji Kawada, Akinori Arimura, Tatsuo Tsuri, +13

Angewandte Chemie International Edition

Proper LinkageImmunologyOrganic ChemistryChemistryHeterocycle Chemistry +15

Total Synthesis of Terprenin, a Novel Immunosuppressive <i>p</i>-Terphenyl Derivative

Shuji Yonezawa, Tadafumi Komurasaki, Kenji Kawada, +11

The Journal of Organic Chemistry

Medicinal ChemistryAntifungal AgentBioorganic ChemistryBiochemistryNatural Sciences +9

Synthesis and Biological Activity of Various Derivatives of a Novel Class of Potent, Selective, and Orally Active Prostaglandin D₂Receptor Antagonists. 1. Bicyclo[2.2.1]heptane Derivatives

Susumu Mitsumori, Tatsuo Tsuri, Tsunetoshi Honma, +9

Journal of Medicinal Chemistry

Bicyclo[2.2.1]heptane and 6,6-Dimethylbicyclo[3.1.1]heptane Derivatives:  Orally Active, Potent, and Selective Prostaglandin D₂ Receptor Antagonists

Tatsuo Tsuri, Tsunetoshi Honma, Yoshiharu Hiramatsu, +9

Journal of Medicinal Chemistry

Altmetric Attention ScorePharmacotherapyExperimental PharmacologyPharmaceutical ChemistryMolecular Pharmacology +14

Practical Diastereoselective Synthesis and Scale-up Study of (+)-2-((1<i>R</i>,2<i>R</i>,3<i>R</i>,5<i>S</i>)-2-Amino-6,6-dimethylbicyclo[3.1.1]hept-3-yl)ethanol: A Key Intermediate of the Novel Prostaglandin D₂Receptor Antagonist S-5751

Takemasa Hida, Susumu Mitsumori, Tsunetoshi Honma, +9

Organic Process Research & Development