Jana Mahadevan

Intermittent fasting preserves beta-cell mass in obesity-induced diabetes via the autophagy-lysosome pathway

Haiyan Liu, Ali Javaheri, Rebecca J. Godar et al. · Autophagy · 2017 · 188 citations · Full text

Cell Death, Fasting, Insulin Signaling +19

Poly-dipeptides encoded by the C9ORF72 repeats block global protein translation

Kohsuke Kanekura, Takuya Yagi, Alexander J. Cammack et al. · Human Molecular Genetics · 2016 · 161 citations · Full text

Protein Function, Alzheimer's Disease, Amyotrophic Lateral Sclerosis +15

A calcium-dependent protease as a potential therapeutic target for Wolfram syndrome

Simin Lu, Kohsuke Kanekura, Takashi Hara et al. · Proceedings of the National Academy of Sciences · 2014 · 148 citations · Full text

Calcium-dependent Protease, Apoptosis, Calpain 2 +25

Calcium Efflux From the Endoplasmic Reticulum Leads to β-Cell Death

Takashi Hara, Jana Mahadevan, Kohsuke Kanekura et al. · Endocrinology · 2014 · 144 citations · Full text

Autosomal Dominant Diabetes Arising From a Wolfram Syndrome 1 Mutation

Lori L. Bonnycastle, Peter S. Chines, Takashi Hara et al. · Diabetes · 2013 · 118 citations · Full text

Wolfram Syndrome 1, Genetics, Genetic Epidemiology +18