William D. Diseroad

Kilogram-scale prexasertib monolactate monohydrate synthesis under continuous-flow CGMP conditions

Kevin P. Cole, Jennifer McClary Groh, Martin D. Johnson et al. · Science · 2017 · 298 citations · Full text

Engineering, Chemical Engineering, Manufacturing Engineering +17

Development and Scale-Up of a Continuous, High-Pressure, Asymmetric Hydrogenation Reaction, Workup, and Isolation

Martin D. Johnson, Scott A. May, Joel R. Calvin et al. · Organic Process Research & Development · 2012 · 148 citations

Engineering, Chemical Engineering, Process Safety +16

Synthesis, Crystallization, and Biological Evaluation of an Orally Active Prodrug of Gemcitabine

David M. Bender, Anne H. Dantzig, William D. Diseroad et al. · Journal of Medicinal Chemistry · 2009 · 107 citations

Pharmacy, Medicinal Chemistry, Pharmacology +16

Diastereomeric Salt Resolution Based Synthesis of LY503430, an AMPA (α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid) Potentiator

Nicholas A. Magnus, James Aikins, Jason S. Cronin et al. · Organic Process Research & Development · 2005 · 23 citations

Pharmacy, Medicinal Chemistry, Pharmacology +16

Synthesis of Imidazole Based p38 MAP (Mitogen-Activated Protein) Kinase Inhibitors under Buffered Conditions

Nicholas A. Magnus, William D. Diseroad, C. Richard Nevill et al. · Organic Process Research & Development · 2006 · 12 citations

Pharmacy, Medicinal Chemistry, Pharmacology +13