Microbial bile acid metabolites modulate gut RORγ+ regulatory T cell homeostasis

Xinyang Song, Ximei Sun, Sungwhan F. Oh, +8

Nature

DysbiosisMucosal ImmunologyBiliary TractMedicineImmunology +6

The microRNA miR-23b suppresses IL-17-associated autoimmune inflammation by targeting TAB2, TAB3 and IKK-α

Shu Zhu, Wen Pan, Xinyang Song, +11

Nature Medicine

InflammationCytokineAutoimmune DiseaseImmunologyImmune Regulation +7

IL-17RE is the functional receptor for IL-17C and mediates mucosal immunity to infection with intestinal pathogens

Xinyang Song, Shu Zhu, Peiqing Shi, +4

Nature Immunology

InflammationIntestinal PathogensMucosal ImmunologyMicrobial PathogensImmunology +5

Dysregulated Lung Commensal Bacteria Drive Interleukin-17B Production to Promote Pulmonary Fibrosis through Their Outer Membrane Vesicles

Daping Yang, Xi Chen, Jingjing Wang, +8

Immunity

InflammationCytokineFibrosisInflammatory Lung DiseaseLung Inflammation +6

Growth Factor FGF2 Cooperates with Interleukin-17 to Repair Intestinal Epithelial Damage

Xinyang Song, Dai Dai, Xiao He, +10

Immunity

InflammationCytokineGrowth Factor Fgf2Mucosal ImmunologyImmunology +7

Bile acids modified by the intestinal microbiota promote colorectal cancer growth by suppressing CD8+ T cell effector functions

Jingjing Cong, Pianpian Liu, Zili Han, +20

Immunity

ProbioticDysbiosisImmunologyGut MicrobiologyPathology +9

Alterations in the Microbiota Drive Interleukin-17C Production from Intestinal Epithelial Cells to Promote Tumorigenesis

Xinyang Song, Hanchao Gao, Yingying Lin, +10

Immunity

InflammationDysbiosisMucosal ImmunologyImmunologyGut Microbiology +9

Microbiota-targeted maternal antibodies protect neonates from enteric infection

Wenfeng Zheng, Wenjing Zhao, Meng Wu, +8

Nature

Maternal ImmunizationMicrobiota-targeted Maternal AntibodiesDysbiosisMicrobiotaGut Microbiology +6

Modulation of experimental autoimmune encephalomyelitis through TRAF3-mediated suppression of interleukin 17 receptor signaling

Shu Zhu, Wen Pan, Peiqing Shi, +8

The Journal of Experimental Medicine

Gut microbial fatty acid isomerization modulates intraepithelial T cells

Xinyang Song, Haohao Zhang, Yanbo Zhang, +12

Nature

InflammationDysbiosisHost-microbe InteractionsImmunologyGut Microbiology +6