Distinct Regulatory Mechanisms and Functions for p53-Activated and p53-Repressed DNA Damage Response Genes in Embryonic Stem Cells

Mangmang Li, Yunlong He, Wendy Dubois, +3

Molecular Cell

Genome InstabilityLineage PlasticityDevelopmental BiologyCell RegulationMedicine +8

A genomewide study identifies the Wnt signaling pathway as a major target of p53 in murine embryonic stem cells

Kyoung Hwa Lee, Mangmang Li, Aleksandra M. Michalowski, +6

Proceedings of the National Academy of Sciences

Embryonic Stem CellGene Expression MicroarraySystems BiologyDevelopmental BiologyP53 Levels +12

Osteoblasts secrete Cxcl9 to regulate angiogenesis in bone

Bin Huang, Wenhao Wang, Qingchu Li, +14

Nature Communications

InflammationBone AngiogenesisSclerostinEndothelial CellsBone Morphogenic Protein +10

An Apela RNA-Containing Negative Feedback Loop Regulates p53-Mediated Apoptosis in Embryonic Stem Cells

Mangmang Li, Hongfeng Gou, Brajendra K. Tripathi, +8

Cell stem cell

Developmental BiologyCell RegulationApoptosisCell DeathLong Non-coding Rna +6

mTORC1 Inhibits NF-κB/NFATc1 Signaling and Prevents Osteoclast Precursor Differentiation, In Vitro and In Mice

Yue Zhang, Song Xu, Kai Li, +13

Journal of Bone and Mineral Research

Mtorc1 ActivityImmunologyImmune RegulationBone RepairRapamycin Complex 1 +18

Tyrosine kinase Fyn promotes osteoarthritis by activating the β-catenin pathway

Kai Li, Yue Zhang, Yuwei Zhang, +11

Annals of the Rheumatic Diseases

Loss of Rictor with aging in osteoblasts promotes age-related bone loss

Pinling Lai, Qiancheng Song, Cheng Yang, +9

Cell Death and Disease

Colonic epithelial mTORC1 promotes ulcerative colitis through COX-2-mediated Th17 responses

Xiaojun Lin, Qiuyi Sun, Ling Zhou, +15

Mucosal Immunology

InflammationMucosal ImmunologyImmunologyGastroenterologyChronic Inflammation +8

hUC-MSC-mediated recovery of subacute spinal cord injury through enhancing the pivotal subunits β3 and γ2 of the GABA_A receptor

Tingting Cao, Huan Chen, Weiping Huang, +10

Theranostics

A modified TMV-based vector facilitates the expression of longer foreign epitopes in tobacco

Lubin Jiang, Qiaoli Li, Mangmang Li, +6

Vaccine

Molecular VirologyPathogenesisImmunologyLonger Foreign EpitopesModified Tmv-based Vector +4