Ubiquitin-Proteasome System Impairment Caused by a Missense Cardiac Myosin-binding Protein C Mutation and Associated with Cardiac Dysfunction in Hypertrophic Cardiomyopathy

Udin Bahrudin, Hiroko Morisaki, Takayuki Morisaki, +12

Journal of Molecular Biology

Cardiac MuscleCardiomyopathyHeart FailureCardiovascular DiseaseMedicine +9

Chemical chaperone therapy: chaperone effect on mutant enzyme and cellular pathophysiology in β-galactosidase deficiency

Katsumi Higaki, Linjing Li, Udin Bahrudin, +17

Human Mutation

Impairment of Ubiquitin–Proteasome System by E334K cMyBPC Modifies Channel Proteins, Leading to Electrophysiological Dysfunction

Udin Bahrudin, Kumi Morikawa, Ayako Takeuchi, +16

Journal of Molecular Biology

Protein FunctionSignal TransductionMolecular PhysiologyUbiquitin–proteasome SystemMedicine +12

Transcriptional activation of the anchoring protein SAP97 by heat shock factor (HSF)‐1 stabilizes K_v1.5 channels in HL‐1 cells

YK Ting, Kumi Morikawa, Yasutaka Kurata, +16

British Journal of Pharmacology

Identification, Isolation and Characterization of HCN4-Positive Pacemaking Cells Derived from Murine Embryonic Stem Cells during Cardiac Differentiation

Kumi Morikawa, Udin Bahrudin, Junichiro Miake, +5

Pacing and Clinical Electrophysiology

Functional stabilization of Kv1.5 protein by Hsp70 in mammalian cell lines

Yutaka Hirota, Yasutaka Kurata, Masaru Kato, +16

Biochemical and Biophysical Research Communications

Functional StabilizationMolecular PhysiologySignal TransductionProtein FunctionMolecular Regulation +10

Apoptosis induced by an uromodulin mutant C112Y and its suppression by topiroxostat

Sulistiyati Bayu Utami, Endang Mahati, Peili Li, +16

Clinical and Experimental Nephrology

Signal TransductionMedicineApoptosisMechanism Of ActionCell Death +8

Changes of HCN gene expression and If currents in Nkx2.5-positive cardiomyocytes derived from murine embryonic stem cells during differentiation

Shuichi Yano, Junichiro Miake, Einosuke Mizuta, +18

Biomedical Research

Hcn 1Cardiac MuscleCardiac Progenitor CellsCell SpecializationCellular Physiology +15

Stabilizing effects of eicosapentaenoic acid on Kv1.5 channel protein expressed in mammalian cells

Shunya Koshida, Yasutaka Kurata, Tomomi Notsu, +16

European Journal of Pharmacology

Cell PhysiologySignal TransductionMolecular PhysiologyBiochemistryHyperpolarization (Biology) +9

Effect of losartan and benzbromarone on the level of human urate transporter 1 mRNA

Yora Nindita, Toshihiro Hamada, Udin Bahrudin, +13

Arzneimittelforschung

Molecular PharmacologyHypertensionUrate Transporter 1Renal FunctionUrological Research +12