Ryan G. Gaudet

Cytosolic detection of the bacterial metabolite HBP activates TIFA-dependent innate immunity

Ryan G. Gaudet, Anna Sintsova, Carolyn M. Buckwalter et al. · Science · 2015 · 154 citations

Microbial Pathogens, Innate Immune System, Immunology +29

TIFA Signaling in Gastric Epithelial Cells Initiates the<i>cag</i>Type 4 Secretion System-Dependent Innate Immune Response to<i>Helicobacter pylori</i>Infection

Alevtina Gall, Ryan G. Gaudet, Scott D. Gray‐Owen et al. · mBio · 2017 · 134 citations · Full text

The heme-regulated inhibitor is a cytosolic sensor of protein misfolding that controls innate immune signaling

Mena Abdel‐Nour, Letícia A. M. Carneiro, Jeffrey Downey et al. · Science · 2019 · 116 citations · Full text

A human apolipoprotein L with detergent-like activity kills intracellular pathogens

Ryan G. Gaudet, Shiwei Zhu, Anushka Halder et al. · Science · 2021 · 101 citations · Full text

Microbial Pathogens, Innate Immune System, Immunology +26

PLSCR1 is a cell-autonomous defence factor against SARS-CoV-2 infection

Dijin Xu, Weiqian Jiang, Lizhen Wu et al. · Nature · 2023 · 93 citations · Full text