The Mitochondrial-Derived Peptide MOTS-c Promotes Metabolic Homeostasis and Reduces Obesity and Insulin Resistance

Changhan Lee, Jennifer Zeng, Brian G. Drew, +8

Cell Metabolism

ObesityMetabolic SyndromeInsulin ResistanceMetabolic DisorderBiochemistry +12

Transcriptional regulation of macrophage cholesterol efflux and atherogenesis by a long noncoding RNA

Tamer Sallam, Marius Jones, Brandon J. Thomas, +20

Nature Medicine

Transcriptional RegulationEngineeringMedicineRna BiologyLong Noncoding Rna +8

Genetic Architecture of Insulin Resistance in the Mouse

Brian W. Parks, Tamer Sallam, Margarete Mehrabian, +18

Cell Metabolism

Insulin ResistanceMetabolic SyndromeKnockout MouseGeneticsDiabetes +4

Feedback modulation of cholesterol metabolism by the lipid-responsive non-coding RNA LeXis

Tamer Sallam, Marius C. Jones, Thomas Gilliland, +11

Nature

Cholesterol MetabolismBiochemistryNatural SciencesRna BiologyMolecular Biology +4

IL-10 Signaling Remodels Adipose Chromatin Architecture to Limit Thermogenesis and Energy Expenditure

Prashant Rajbhandari, Brandon J. Thomas, An-Chieh Feng, +15

Cell

ObesityChromatinEnergy HomeostasisEnergy MetabolismLimit Thermogenesis +10

Inhibition of cholesterol biosynthesis through RNF145-dependent ubiquitination of SCAP

Li Zhang, Prashant Rajbhandari, Christina Priest, +7

eLife

Cholesterol BiosynthesisSignal TransductionMolecular PhysiologyBiochemistrySignaling Pathway +12

RNA-binding protein ZFP36L1 maintains posttranscriptional regulation of bile acid metabolism

Elizabeth J. Tarling, Bethan L. Clifford, Joan Cheng, +6

Journal of Clinical Investigation

Bile Acid HomeostasisFatty Liver DiseaseCholangiopathiesRna-binding Protein Zfp36l1Metabolic Syndrome +17

DDX17 is an essential mediator of sterile NLRC4 inflammasome activation by retrotransposon RNAs

Shao-Bin Wang, Siddharth Narendran, Shuichiro Hirahara, +21

Science Immunology

ImmunologyCell DeathInnate ImmunityImmune SystemInflammation +17

Cathelicidin suppresses lipid accumulation and hepatic steatosis by inhibition of the CD36 receptor

Deanna Tran, Dieu Tran, S. Anjani Mattai, +22

International Journal of Obesity

HepatologyBiochemistryLipid AccumulationMedicineLiver Physiology +10

RNA-binding protein PSPC1 promotes the differentiation-dependent nuclear export of adipocyte RNAs

Jiexin Wang, Prashant Rajbhandari, Andrey Damianov, +13

Journal of Clinical Investigation