Brendan Horton - Concepedia

Author

Brendan Horton

University of Chicago ORCID

Also Known As

BRENDAN HORTON, BRENDAN> HORTON>, Brendan Horton, Brendan L Horton, Brendan L. Horton, Craig L. Slingluff

123

Publications

3.2K

Citations

H-Index

Concepts

All Affiliations

University of Chicago Massachusetts Institute of Technology IIT@MIT Harvard University Dana-Farber Cancer Institute

About

Brendan Horton is an author at University of Chicago specializing in medicine, immunology, and cell biology.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	8	8	1.7K
2	Cell Biology	4	4	1.6K
3	Immunology	4	4	1.5K
4	Engineering	1	1	55
5	Allergy	1	1	23

Brendan Horton

Publications

2.8K

Citations

H-Index

Page 1

	Year	Citations
Tumor-Residing Batf3 Dendritic Cells Are Required for Effector T Cell Trafficking and Adoptive T Cell Therapy Stefani Spranger, Daisy Dai, Brendan Horton, Cancer Cell Cancer ImmunosurveillanceImmunologyImmunoeditingCell BiologyImmune Cell Therapy	2017	1.4K
Mechanism of tumor rejection with doublets of CTLA-4, PD-1/PD-L1, or IDO blockade involves restored IL-2 production and proliferation of CD8+ T cells directly within the tumor microenvironment Stefani Spranger, Holly K. Koblish, Brendan Horton, Journal for ImmunoTherapy of Cancer	2014	535
The EGR2 targets LAG-3 and 4-1BB describe and regulate dysfunctional antigen-specific CD8+ T cells in the tumor microenvironment Jason B. Williams, Brendan Horton, Yan Zheng, The Journal of Experimental Medicine	2017	205
Intratumoral CD8+ T-cell Apoptosis Is a Major Component of T-cell Dysfunction and Impedes Antitumor Immunity Brendan Horton, Jason B. Williams, Alexandra Cabanov, Cancer Immunology Research	2017	163
Tissue-specific abundance of interferon-gamma drives regulatory T cells to restrain DC1-mediated priming of cytotoxic T cells against lung cancer Maria Zagorulya, Leon Yim, Duncan M. Morgan, Immunity Cancer ImmunosurveillanceLung InflammationDc1-mediated PrimingT-regulatory CellImmunology	2023	132
Lack of CD8 <sup>+</sup> T cell effector differentiation during priming mediates checkpoint blockade resistance in non–small cell lung cancer Brendan Horton, Duncan M. Morgan, Noor Momin, Science Immunology	2021	125
A prime editor mouse to model a broad spectrum of somatic mutations in vivo Zackery A. Ely, Nicolas Mathey‐Andrews, Santiago Naranjo, Nature Biotechnology Knockout MouseXenotransplantationDevelopmental BiologyTransgenic Mouse ModelsSomatic Mutations	2023	55
Formation of Human Neuroblastoma in Mouse-Human Neural Crest Chimeras Malkiel A. Cohen, Shupei Zhang, Satyaki Sengupta, Cell stem cell Human NeuroblastomaGliomaEpendymaHistopathologyPathology	2020	46
Expansion of tumor-reactive CD8 <sup>+</sup> T cell clonotypes occurs in the spleen in response to immune checkpoint blockade Duncan M. Morgan, Brendan Horton, Vidit Bhandarkar, Science Immunology	2024	38
Overcoming lung cancer immunotherapy resistance by combining nontoxic variants of IL-12 and IL-2 Brendan Horton, Alicia D. D’Souza, Maria Zagorulya, JCI Insight Lung TumorsCancer ImmunosurveillanceAllergyNontoxic VariantsLow Il-12 Receptor	2023	23

Page 1