Žaklina Kovačević

The Iron Chelators Dp44mT and DFO Inhibit TGF-β-induced Epithelial-Mesenchymal Transition via Up-Regulation of N-Myc Downstream-regulated Gene 1 (NDRG1)

Zhiqiang Chen, Daohai Zhang, Fei Yue et al. · Journal of Biological Chemistry · 2012 · 247 citations · Full text

Transcriptional Regulation, Signaling Pathway, Cell Regulation +8

The role of glutamine in the oxidative metabolism of malignant cells.

Žaklina Kovačević, H. P. Morris · PubMed · 1972 · 225 citations

Oxidative Metabolism, Redox Biology, Tumor Biology +20

Novel Thiosemicarbazone Iron Chelators Induce Up-Regulation and Phosphorylation of the Metastasis Suppressor N-myc Down-Stream Regulated Gene 1: A New Strategy for the Treatment of Pancreatic Cancer

Žaklina Kovačević, Sherin Chikhani, David B. Lovejoy et al. · Molecular Pharmacology · 2011 · 174 citations

The Iron-Regulated Metastasis Suppressor NDRG1 Targets NEDD4L, PTEN, and SMAD4 and Inhibits the PI3K and Ras Signaling Pathways

Žaklina Kovačević, Sherin Chikhani, Goldie Y.L. Lui et al. · Antioxidants and Redox Signaling · 2012 · 166 citations

The Iron Chelator, Deferasirox, as a Novel Strategy for Cancer Treatment: Oral Activity Against Human Lung Tumor Xenografts and Molecular Mechanism of Action

Goldie Y.L. Lui, Peyman Obeidy, Samuel Ford et al. · Molecular Pharmacology · 2012 · 135 citations