Concepedia

Novel Thiosemicarbazone Iron Chelators Induce Up-Regulation and Phosphorylation of the Metastasis Suppressor N-myc Down-Stream Regulated Gene 1: A New Strategy for the Treatment of Pancreatic Cancer

Žaklina Kovačević, Sherin Chikhani, David B. Lovejoy, Des R. Richardson

Molecular Pharmacology · 2011 · 174 citations · 31 references

References

31

Cancer Statistics, 2009

Ahmedin Jemal, Rebecca L. Siegel, Elizabeth Ward et al. · CA A Cancer Journal for Clinicians · 2009 · 9.7K citations · Full text

Medicine, Oncology, Cancer Epidemiology +16

The p21Cip1 and p27Kip1 CDK ‘inhibitors’ are essential activators of cyclin D‐dependent kinases in murine fibroblasts

Mangeng Cheng, Paul Olivier, J. Alan Diehl et al. · The EMBO Journal · 1999 · 1.1K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +15

Curcumin Potentiates Antitumor Activity of Gemcitabine in an Orthotopic Model of Pancreatic Cancer through Suppression of Proliferation, Angiogenesis, and Inhibition of Nuclear Factor-κB–Regulated Gene Products

Ajaikumar B. Kunnumakkara, Sushovan Guha, Sunil Krishnan et al. · Cancer Research · 2007 · 579 citations · Full text

Medicine, Oncology, Pharmacology +16

A class of iron chelators with a wide spectrum of potent antitumor activity that overcomes resistance to chemotherapeutics

Megan Whitnall, Jonathan Howard, Prem Ponka et al. · Proceedings of the National Academy of Sciences · 2006 · 508 citations

Medicine, Oncology, Pharmacology +13

Novel di-2-pyridyl–derived iron chelators with marked and selective antitumor activity: in vitro and in vivo assessment

Jun Yuan, David B. Lovejoy, Des R. Richardson · Blood · 2004 · 384 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +9