Jaclyn S. Long

Bromodomain Protein BRD4 Is a Transcriptional Repressor of Autophagy and Lysosomal Function

Jun-Ichi Sakamaki, Simon Wilkinson, Marcel Hahn et al. · Molecular Cell · 2017 · 242 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

FTY720 and (S)-FTY720 vinylphosphonate inhibit sphingosine kinase 1 and promote its proteasomal degradation in human pulmonary artery smooth muscle, breast cancer and androgen-independent prostate cancer cells

Francesca Tonelli, Keng Gat Lim, Carolyn J. Loveridge et al. · Cellular Signalling · 2010 · 179 citations · Full text

Life Sciences, Biochemistry, Cell Biology +16

High Expression of Sphingosine 1-Phosphate Receptors, S1P1 and S1P3, Sphingosine Kinase 1, and Extracellular Signal-Regulated Kinase-1/2 Is Associated with Development of Tamoxifen Resistance in Estrogen Receptor-Positive Breast Cancer Patients

Carol Watson, Jaclyn S. Long, Clare Orange et al. · American Journal Of Pathology · 2010 · 169 citations · Full text

Life Sciences, Molecular Biology, Oncology +17

Loss of autophagy causes a synthetic lethal deficiency in DNA repair

Emma Y. Liu, Naihan Xu, Jim O’Prey et al. · Proceedings of the National Academy of Sciences · 2015 · 160 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

The Sphingosine Kinase 1 Inhibitor 2-(p-Hydroxyanilino)-4-(p-chlorophenyl)thiazole Induces Proteasomal Degradation of Sphingosine Kinase 1 in Mammalian Cells

Carolyn J. Loveridge, Francesca Tonelli, Tamara Leclercq et al. · Journal of Biological Chemistry · 2010 · 117 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +14