Yoshitaka Isaka

Autophagy sequesters damaged lysosomes to control lysosomal biogenesis and kidney injury

Ikuko Maejima, Atsushi Takahashi, Hiroko Omori et al. · The EMBO Journal · 2013 · 620 citations · Full text

Cell Autophagy, Mitophagy, Lysosomal Biogenesis +12

Glomerulosclerosis induced by in vivo transfection of transforming growth factor-beta or platelet-derived growth factor gene into the rat kidney.

Yoshitaka Isaka, Y. Fujiwara, Naohiko Ueda et al. · Journal of Clinical Investigation · 1993 · 531 citations · Full text

Glomerular Disease, Renal Pathology, Immunology +23

Gene therapy by skeletal muscle expression of decorin prevents fibrotic disease in rat kidney

Yoshitaka Isaka, Douglas K. Brees, Kazuko Ikegaya et al. · Nature Medicine · 1996 · 486 citations

Regenerative Medicine, Mechanobiology, Gene Therapies +13

Autophagy Protects the Proximal Tubule from Degeneration and Acute Ischemic Injury

Tomonori Kimura, Yoshitsugu Takabatake, Atsushi Takahashi et al. · Journal of the American Society of Nephrology · 2011 · 448 citations · Full text

Mitophagy, Apoptosis, Immunology +27

Dialysis initiation, modality choice, access, and prescription: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference

Christopher T. Chan, Peter J. Blankestijn, Laura M. Dember et al. · Kidney International · 2019 · 404 citations · Full text

Hemodialysis, Renal Disease, Health Policy +13