Robbert H. Cool

Epac is a Rap1 guanine-nucleotide-exchange factor directly activated by cyclic AMP

Johan de Rooij, Fried Zwartkruis, Mark H. G. Verheijen et al. · Nature · 1998 · 2K citations

Signal Transduction, Molecular Physiology, Biochemistry +7

Mechanism of Regulation of the Epac Family of cAMP-dependent RapGEFs

Johan de Rooij, Holger Rehmann, Miranda van Triest et al. · Journal of Biological Chemistry · 2000 · 396 citations · Full text

Quorum Quenching by an <i>N</i> -Acyl-Homoserine Lactone Acylase from <i>Pseudomonas aeruginosa</i> PAO1

Charles F. Sio, Linda G. Otten, Robbert H. Cool et al. · Infection and Immunity · 2006 · 311 citations · Full text

Kinetic Analysis by Fluorescence of the Interaction between Ras and the Catalytic Domain of the Guanine Nucleotide Exchange Factor Cdc25^Mm

Christian Lenzen, Robbert H. Cool, Heino Prinz et al. · Biochemistry · 1998 · 222 citations

Catalytic Domain, Nucleic Acid Chemistry, Signal Transduction +13

Designed tumor necrosis factor-related apoptosis-inducing ligand variants initiating apoptosis exclusively via the DR5 receptor

Almer M. van der Sloot, Vicente Tur, Éva Szegezdi et al. · Proceedings of the National Academy of Sciences · 2006 · 168 citations · Full text

Apoptosis, Immunology, Cell Death +17