Personalized <i>In Vitro</i> and <i>In Vivo</i> Cancer Models to Guide Precision Medicine

Chantal Pauli, Benjamin D. Hopkins, Davide Prandi, +26

Cancer Discovery

Recurrence patterns across medulloblastoma subgroups: an integrated clinical and molecular analysis

Vijay Ramaswamy, Marc Remke, Éric Bouffet, +40

The Lancet Oncology

Neuro-oncologyTumoral PathologyOncologyTumor HeterogeneityRecurrence Patterns +6

Disulfiram, a drug widely used to control alcoholism, suppresses self-renewal of glioblastoma and overrides resistance to temozolomide

Joanna Triscott, Cathy Lee, Kaiji Hu, +10

Oncotarget

Personalizing the Treatment of Pediatric Medulloblastoma: Polo-like Kinase 1 as a Molecular Target in High-Risk Children

Joanna Triscott, Cathy Lee, Colleen Foster, +18

Cancer Research

YB-1 Bridges Neural Stem Cells and Brain Tumor–Initiating Cells via Its Roles in Differentiation and Cell Growth

Abbas Fotovati, Samah Abu‐Ali, Pei-Shan Wang, +17

Cancer Research

Cell GrowthStem Cell BiologyGliomaTumor BiologySocial Sciences +18

Polo-Like Kinase 1 Inhibition Kills Glioblastoma Multiforme Brain Tumor Cells in Part Through Loss of SOX2 and Delays Tumor Progression in Mice

Cathy Lee, Abbas Fotovati, Joanna Triscott, +13

Stem Cells

Cell DeathPathologyHigh-grade GliomasCancer BiologyGlioma +17

Overcoming resistance to sonic hedgehog inhibition by targeting p90 ribosomal S6 kinase in pediatric medulloblastoma

Mary Rose Pambid, Rachel Berns, Hans Adomat, +10

Pediatric Blood & Cancer

FoxG1 Interacts with Bmi1 to Regulate Self-Renewal and Tumorigenicity of Medulloblastoma Stem Cells

Branavan Manoranjan, Xin Wang, Robin Hallett, +14

Stem Cells

PI5P4Ks drive metabolic homeostasis through peroxisome-mitochondria interplay

Archna Ravi, Lavinia Palamiuc, Ryan M. Loughran, +12

Developmental Cell

Peroxisome-mitochondria InterplayMitochondrial FunctionPhysiologyMetabolismMedicine +1

Deep Sequencing Identifies <i>IDH1</i> R132S Mutation in Adult Medulloblastoma

Matija Snuderl, Joanna Triscott, Paul A. Northcott, +6

Journal of Clinical Oncology

MedicineGeneticsMolecular GeneticsAdult MedulloblastomaGenomics +2