B Cell Receptor-Mediated Internalization of <i>Salmonella</i>: A Novel Pathway for Autonomous B Cell Activation and Antibody Production

Yuri Souwer, Alexander Griekspoor, Tineke Jorritsma, +4

The Journal of Immunology

Microbial PathogensAdaptive Immune SystemNovel PathwayInnate Immune SystemImmunology +17

Class II-Associated Invariant Chain Peptide Expression on Myeloid Leukemic Blasts Predicts Poor Clinical Outcome

Martine E.D. Chamuleau, Yuri Souwer, S. Marieke van Ham, +6

Cancer Research

Antigen-Specific B Cells Reactivate an Effective Cytotoxic T Cell Response against Phagocytosed Salmonella through Cross-Presentation

Jelle de Wit, Yuri Souwer, Tineke Jorritsma, +4

PLoS ONE

Acetylcholine-producing T cells in the intestine regulate antimicrobial peptide expression and microbial diversity

Shobhit Dhawan, Giada De Palma, Rose Willemze, +13

American Journal of Physiology-Gastrointestinal and Liver Physiology

CD5 costimulation induces stable Th17 development by promoting IL-23R expression and sustained STAT3 activation

Jelle de Wit, Yuri Souwer, Astrid J. van Beelen, +7

Blood

Selective Infection of Antigen-Specific B Lymphocytes by Salmonella Mediates Bacterial Survival and Systemic Spreading of Infection

Yuri Souwer, Alexander Griekspoor, Jelle de Wit, +7

PLoS ONE

Human B cells promote T-cell plasticity to optimize antibody response by inducing coexpression of TH1/TFH signatures

Jelle de Wit, Tineke Jorritsma, Mateusz Makuch, +6

Journal of Allergy and Clinical Immunology

Systems BiologyAutoimmune DiseaseHuman B CellsT-cell PlasticityT-regulatory Cell +9

Class II-associated invariant chain peptide down-modulation enhances the immunogenicity of myeloid leukemic blasts resulting in increased CD4+ T-cell responses

Marvin M. van Luijn, Martine E.D. Chamuleau, James A. Thompson, +6

Haematologica

Detection of aberrant transcription of major histocompatibility complex class II antigen presentation genes in chronic lymphocytic leukaemia identifies <i>HLA‐DOA</i> mRNA as a prognostic factor for survival

Yuri Souwer, Martine E.D. Chamuleau, Arjan A. van de Loosdrecht, +10

British Journal of Haematology

HistocompatibilityHlaHla ImmunogeneticsImmunologyPathology +19

Alternative Ii-independent antigen-processing pathway in leukemic blasts involves TAP-dependent peptide loading of HLA class II complexes

Marvin M. van Luijn, Martine E.D. Chamuleau, Maaike E. Ressing, +7

Cancer Immunology Immunotherapy