A subset of group A-like <i>var</i> genes encodes the malaria parasite ligands for binding to human brain endothelial cells

Antoine Claessens, Yvonne Adams, Ashfaq Ghumra, +12

Proceedings of the National Academy of Sciences

Plasmodium FalciparumMalariaImmunologyHematologyPathogenesis +13

Induction of Strain-Transcending Antibodies Against Group A PfEMP1 Surface Antigens from Virulent Malaria Parasites

Ashfaq Ghumra, Jean‐Philippe Semblat, Ricardo Ataíde, +14

PLoS Pathogens

Microbial PathogensMalariaImmunologyInnate ImmunityPlasmodium Falciparum +16

Rosetting Plasmodium falciparum-Infected Erythrocytes Bind to Human Brain Microvascular Endothelial Cells <i>In Vitro</i> , Demonstrating a Dual Adhesion Phenotype Mediated by Distinct P. falciparum Erythrocyte Membrane Protein 1 Domains

Yvonne Adams, Pongsak Kuhnrae, Matthew K. Higgins, +2

Infection and Immunity

Identification of Residues in the Cμ4 Domain of Polymeric IgM Essential for Interaction with <i>Plasmodium falciparum</i> Erythrocyte Membrane Protein 1 (PfEMP1)

Ashfaq Ghumra, Jean‐Philippe Semblat, Richard S. McIntosh, +8

The Journal of Immunology

Immunisation with Recombinant PfEMP1 Domains Elicits Functional Rosette-Inhibiting and Phagocytosis-Inducing Antibodies to Plasmodium falciparum

Ashfaq Ghumra, Pongsak Khunrae, Ricardo Ataíde, +4

PLoS ONE

Structural requirements for the interaction of human IgM and IgA with the human Fcα/μ receptor

Ashfaq Ghumra, Jianguo Shi, Richard S. McIntosh, +10

European Journal of Immunology

Structural FeaturesProtein FunctionSignal TransductionStructural RequirementsImmunology +11

Proteases from Schistosoma mansoni cercariae cleave IgE at solvent exposed interdomain regions

Akhmed Aslam, P M Quinn, Richard S. McIntosh, +9

Molecular Immunology

Parasitic DiseaseSchistosoma Mansoni CercariaeParasitic ProtozoaMedicineNatural Sciences +7

Mechanistic Studies of the Negative Epistatic Malaria-protective Interaction Between Sickle Cell Trait and α+thalassemia

D. Herbert Opi, Lucy Ochola, Metrine Tendwa, +7

EBioMedicine

Infected erythrocytes expressing DC13 PfEMP1 differ from recombinant proteins in EPCR-binding function

Yvonne Azasi, Gabriella Lindergard, Ashfaq Ghumra, +3

Proceedings of the National Academy of Sciences

Design of a variant surface antigen-supplemented microarray chip for whole transcriptome analysis of multiple Plasmodium falciparum cytoadherent strains, and identification of strain-transcendent rif and stevor genes

Antoine Claessens, Ashfaq Ghumra, Archna P. Gupta, +3

Malaria Journal