Concepedia

Jason Shirian

JS

7

Publications

287

Citations

7

H-Index

2014

Active since

Affiliations

Hebrew University of Jerusalem(Current)

Ben-Gurion University of the Negev

Weizmann Institute of Science

Mayo Clinic in Florida

Sylvester Comprehensive Cancer Center

Jason Shirian is an author at Hebrew University of Jerusalem specializing in molecular biology, natural sciences, and medicine.

Top concepts

Natural SciencesMolecular BiologyMedicineSystems BiologyBiochemistryCell BiologyCell SignalingProtein FoldingProtein AssemblyMolecular Docking

Publications per year

2014–2021

7

Publications

7

Development of High Affinity and High Specificity Inhibitors of Matrix Metalloproteinase 14 through Computational Design and Directed Evolution

Valeria Arkadash, Gal Yosef, Jason Shirian et al. · Journal of Biological Chemistry · 2017 · 80 citations · Full text

Biochemistry, Biomolecular Structure Prediction, Natural Sciences +13

Affinity- and Specificity-Enhancing Mutations Are Frequent in Multispecific Interactions between TIMP2 and MMPs

Oz Sharabi, Jason Shirian, Moran Grossman et al. · PLoS ONE · 2014 · 52 citations · Full text

Genetics, Genomic Mechanism, Molecular Biology +18

Converting a broad matrix metalloproteinase family inhibitor into a specific inhibitor of <scp>MMP</scp> ‐9 and <scp>MMP</scp> ‐14

Jason Shirian, Valeria Arkadash, Itay Cohen et al. · FEBS Letters · 2018 · 47 citations · Full text

Cold Spots in Protein Binding

Jason Shirian, Oz Sharabi, Julia M. Shifman · Trends in Biochemical Sciences · 2016 · 34 citations

Protein Chemistry, Protein Assembly, Biochemistry +5

Climbing Up and Down Binding Landscapes through Deep Mutational Scanning of Three Homologous Protein–Protein Complexes

Michael Heyne, Jason Shirian, Itay Cohen et al. · Journal of the American Chemical Society · 2021 · 34 citations · Full text

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