Concepedia

Author

Yasuyuki Mitani

Astellas Pharma (Japan)

Also Known As

Yasuyuki Mitani

15

Publications

540

Citations

10

H-Index

21

Concepts

All Affiliations

Astellas Pharma (Japan)Cincinnati Children's Hospital Medical Center
YM

About

Yasuyuki Mitani is an author at Astellas Pharma (Japan) specializing in drug discovery, neurodegenerative diseases, and neuropharmacology.

Top Concepts

#ConceptH-IndexPublicationsCitations

1

Medicine

2

2

33

2

Biochemistry

2

2

30

3

Natural Sciences

1

1

15

4

Social Sciences

1

1

18

5

Chemical Biology

1

1

15

Yasuyuki Mitani

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8

Publications

434

Citations

8

H-Index

YearCitations

Differential Effects between γ-Secretase Inhibitors and Modulators on Cognitive Function in Amyloid Precursor Protein-Transgenic and Nontransgenic Mice

Yasuyuki Mitani, Junko Yarimizu, Kyoko Saita,

Journal of Neuroscience

2012

194

Structure–function analysis of myomaker domains required for myoblast fusion

Douglas P. Millay, Dilani G. Gamage, Malgorzata E. Quinn,

Proceedings of the National Academy of Sciences

2016

83

Pharmacological Characterization of a Novel, Potent Adenosine A1 and A2A Receptor Dual Antagonist, 5-[5-Amino-3-(4-fluorophenyl)pyrazin-2-yl]-1-isopropylpyridine-2(1 H)-one (ASP5854), in Models of Parkinson’s Disease and Cognition

Takuma Mihara, Kayoko Mihara, Junko Yarimizu,

Journal of Pharmacology and Experimental Therapeutics

2007

75

Amelioration of cognitive deficits in plaque‐bearing <scp>A</scp>lzheimer's disease model mice through selective reduction of nascent soluble A42 without affecting other A pools

Yasuyuki Mitani, Junko Yarimizu, Hiroki Akashiba,

Journal of Neurochemistry

2012

18

Stereoselective Metabolism of Cibenzoline, an Antiarrhythmic Drug, by Human and Rat Liver Microsomes: Possible Involvement of CYP2D and CYP3A

Toshiro Niwa, Toshifumi Shiraga, Yasuyuki Mitani,

Drug Metabolism and Disposition

2000

18

In <i>vivo</i> myomaker‐mediated heterologous fusion and nuclear reprogramming

Yasuyuki Mitani, Ronald J. Vagnozzi, Douglas P. Millay

The FASEB Journal

2016

16

Discovery of novel scaffolds for γ-secretase modulators without an arylimidazole moiety

Ryuichi Sekioka, Eriko Honjo, Shugo Honda,

Bioorganic & Medicinal Chemistry

2017

15

Optimization and biological evaluation of imidazopyridine derivatives as a novel scaffold for γ-secretase modulators with oral efficacy against cognitive deficits in Alzheimer’s disease model mice

Ryuichi Sekioka, Shugo Honda, Hiroki Akashiba,

Bioorganic & Medicinal Chemistry

2020

15

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