Akihito Fujii

Discovery of furan-2-carbohydrazides as orally active glucagon receptor antagonists

Futoshi Hasegawa, Kazumi Niidome, Chiaki Migihashi et al. · Bioorganic & Medicinal Chemistry Letters · 2014 · 66 citations · Full text

Medicinal Chemistry, Biochemistry, G Protein-coupled Receptor +7

Asymmetric 1,3-dipolar cycloaddition of chiral sulphinylethenes with 1-methyl-3-oxido-pyridinium and some nitrones

Tamiko Takahashi, Akihito Fujii, Jun Sugita et al. · Tetrahedron Asymmetry · 1991 · 50 citations

Heterocyclic, Chiral Sulphinylethenes, Asymmetric 1,3-Dipolar Cycloaddition +5

Stereospecific recognition of a spirosuccinimide type aldose reductase inhibitor (AS-3201) by plasma proteins: A significant role of specific binding by serum albumin in the improved potency and stability

Masuo Kurono, Akihito Fujii, Makoto Murata et al. · Biochemical Pharmacology · 2005 · 41 citations

Aldo-keto Reductase, Serum Albumin, Biochemistry +9

Stereocontrol in intermolecular nucleophilic addition to N-acyliminium ion directed by a bicyclo(2.2.1)heptene or 7-oxabicyclo(2.2.1)heptene group. A novel route to 5-substituted 3-pyrrolin-2-ones of high optical purity.

Yoshitsugu Arai, Akihito Fujii, Toshiyuki Ohno et al. · Chemical and Pharmaceutical Bulletin · 1992 · 23 citations · Full text

N-acyliminium Ion, Engineering, Heterocyclic +11

Asymmetric Diels–Alder reaction of optically active α-(2-exo-hydroxy-10-bornyl)sulfinylmaleimides and its application to optically active 5-functionalised pyrrolines via retro-Diels–Alder reaction

Yoshitsugu Arai, Makoto Matsui, Akihito Fujii et al. · Journal of the Chemical Society Perkin Transactions 1 · 1994 · 23 citations

Engineering, Sulfoxides 1, Various Dienes +10