Dynamic competition between SARS-CoV-2 NSP1 and mRNA on the human ribosome inhibits translation initiation

Christopher P. Lapointe, Rosslyn Grosely, Alex G. Johnson, +3

Proceedings of the National Academy of Sciences

RPS25 is required for efficient RAN translation of C9orf72 and other neurodegenerative disease-associated nucleotide repeats

Shizuka Yamada, Tania F. Gendron, Teresa Niccoli, +17

Nature Neuroscience

Neurodegenerative DiseasesNatural SciencesGeneticsMolecular BiologyDna Replication +7

A novel quantitative microarray antibody capture assay identifies an extremely high hepatitis delta virus prevalence among hepatitis B virus–infected mongolians

Xiaohua Chen, Odgerel Oidovsambuu, Ping Liu, +13

Hepatology

Multiple Parallel Pathways of Translation Initiation on the CrPV IRES

Alexey Petrov, Rosslyn Grosely, Jin Chen, +2

Molecular Cell

Viral ReplicationNatural SciencesDna ReplicationMolecular BiologyVirus Gene +4

eIF5B and eIF1A reorient initiator tRNA to allow ribosomal subunit joining

Christopher P. Lapointe, Rosslyn Grosely, Masaaki Sokabe, +9

Nature

Ribosomal Subunit JoiningRna BiologyMolecular BiologyMolecular GeneticsMedicine +4

Effects of Phosphorylation on the Structure and Backbone Dynamics of the Intrinsically Disordered Connexin43 C-terminal Domain

Rosslyn Grosely, Jennifer L. Kopanic, Sarah Nabors, +5

Journal of Biological Chemistry

Dynamic competition between SARS-CoV-2 NSP1 and mRNA on the human ribosome inhibits translation initiation

Christopher P. Lapointe, Rosslyn Grosely, Alex G. Johnson, +3

Viral ReplicationSystems BiologyTranslational BiologySars-cov-2 Nsp1Translation Initiation +11

Structural Studies of the Nedd4 WW Domains and Their Selectivity for the Connexin43 (Cx43) Carboxyl Terminus

Gaëlle Spagnol, Fabien Kieken, Jennifer L. Kopanic, +5

Journal of Biological Chemistry

Fluorescently-tagged human eIF3 for single-molecule spectroscopy

Alex G. Johnson, Alexey Petrov, Gabriele Fuchs, +4

Nucleic Acids Research

EngineeringMolecular BiologyComplex SystemsProtein SynthesisFluorescently-tagged Human Eif3 +15

Inhibition of insulin-like growth factor II (IGF-II)-dependent cell growth by multidentate pentamannosyl 6-phosphate-based ligands targeting the mannose 6-phosphate/IGF-II receptor

Megan E. Zavorka, Christopher M. Connelly, Rosslyn Grosely, +1

Oncotarget

EngineeringHuman GrowthMannose 6-Phosphate/igf-ii Receptor-Dependent Cell GrowthInsulin Signaling +21