Sustained ERK inhibition maximizes responses of BrafV600E thyroid cancers to radioiodine

James Nagarajah, Mina Le, Jeffrey A. Knauf, +15

Journal of Clinical Investigation

EngineeringErk InhibitionTumor BiologyBraf-mutant Thyroid CancerOncology +18

Pathogenesis of hypothyroidism-induced NAFLD is driven by intra- and extrahepatic mechanisms

Giuseppe Ferrandino, Rachel R. Kaspari, Olga Spadaro, +7

Proceedings of the National Academy of Sciences

Extrahepatic MechanismsImmunologyFatty Liver DiseaseInsulin SignalingAdipose Tissue Lipolysis +18

Breath Biopsy Assessment of Liver Disease Using an Exogenous Volatile Organic Compound—Toward Improved Detection of Liver Impairment

Giuseppe Ferrandino, Isabel Orf, Rob Smith, +15

Clinical and Translational Gastroenterology

An extremely high dietary iodide supply forestalls severe hypothyroidism in Na+/I− symporter (NIS) knockout mice

Giuseppe Ferrandino, Rachel R. Kaspari, Andrea Reyna‐Neyra, +3

Scientific Reports

Na ⁺ coordination at the Na2 site of the Na ⁺ /I ⁻ symporter

Giuseppe Ferrandino, Juan P. Nicola, Yuly E. Sánchez, +4

Proceedings of the National Academy of Sciences

A Locus on Mouse Chromosome 2 Is Involved in Susceptibility to Congenital Hypothyroidism and Contains an Essential Gene Expressed in Thyroid

Elena Amendola, Remo Sanges, Antonella Galvan, +10

Endocrinology

GeneticsGenomic MechanismMolecular BiologyMolecular GeneticsEssential Gene +16

DNAJC17 is localized in nuclear speckles and interacts with splicing machinery components

Antonia Pascarella, Giuseppe Ferrandino, Sara Carmela Credendino, +11

Scientific Reports

Nuclear SpecklesGeneticsRna SplicingMolecular BiologyGene Characterization +18

Breath Biopsy^® to Identify Exhaled Volatile Organic Compounds Biomarkers for Liver Cirrhosis Detection

Giuseppe Ferrandino, Giovanna De Palo, Antonio Murgia, +16

Journal of Clinical and Translational Hepatology

Exogenous Volatile Organic Compound (EVOC®) Breath Testing Maximizes Classification Performance for Subjects with Cirrhosis and Reveals Signs of Portal Hypertension

Giuseppe Ferrandino, Federico Ricciardi, Antonio Murgia, +17

Biomedicines