Iraz T. Aydin

FBXW7 modulates cellular stress response and metastatic potential through HSF1 post-translational modification

Nikos Kourtis, Rana S. Moubarak, Beatriz Aranda-Orgillés et al. · Nature Cell Biology · 2015 · 155 citations · Full text

Signaling Pathway, Cell Regulation, Hsf1 Post-translational Modification +7

FBXW7 Mutations in Melanoma and a New Therapeutic Paradigm

Iraz T. Aydin, Rachel Melamed, Sarah J. Adams et al. · JNCI Journal of the National Cancer Institute · 2014 · 93 citations · Full text

Transcriptional dissection of melanoma identifies a high-risk subtype underlying TP53 family genes and epigenome deregulation

Brateil Badal, Alexander Solovyov, Serena Di Cecilia et al. · JCI Insight · 2017 · 68 citations · Full text

Genomic Characterization of Dysplastic Nevi Unveils Implications for Diagnosis of Melanoma

Rachel Melamed, Iraz T. Aydin, Geena Susan Rajan et al. · Journal of Investigative Dermatology · 2016 · 57 citations

Genomic Characterization, Tumor Heterogeneity, Medicine +11

RBP-Jκ-dependent Notch signaling enhances retinal pigment epithelial cell proliferation in transgenic mice

Karine Schouwey, Iraz T. Aydin, Freddy Radtke et al. · Oncogene · 2010 · 36 citations · Full text

Developmental Biology, Signal Transduction, Ophthalmology +8