Shinya Tokuhiro

Functional haplotypes of PADI4, encoding citrullinating enzyme peptidylarginine deiminase 4, are associated with rheumatoid arthritis

Akari Suzuki, Ryo Yamada, Xiaotian Chang et al. · Nature Genetics · 2003 · 1.2K citations

Rheumatoid Disorder, Rheumatology, Functional Haplotypes +8

An intronic SNP in a RUNX1 binding site of SLC22A4, encoding an organic cation transporter, is associated with rheumatoid arthritis

Shinya Tokuhiro, Ryo Yamada, Xiaotian Chang et al. · Nature Genetics · 2003 · 639 citations

Rheumatoid Disorder, Rheumatology, Organic Cation Transporter +8

A functional variant in FCRL3, encoding Fc receptor-like 3, is associated with rheumatoid arthritis and several autoimmunities

Yuta Kochi, Ryo Yamada, Akari Suzuki et al. · Nature Genetics · 2005 · 409 citations · Full text

Inflammation, Rheumatology, Rheumatoid Disorder +11

The presenilin 2 mutation (N141I) linked to familial Alzheimer disease (Volga German families) increases the secretion of amyloid β protein ending at the 42nd (or 43rd) residue

Taisuke Tomita, Kei Maruyama, Takaomi C. Saido et al. · Proceedings of the National Academy of Sciences · 1997 · 372 citations · Full text

SORCS1 alters amyloid precursor protein processing and variants may increase Alzheimer's disease risk

Christiane Reitz, Shinya Tokuhiro, Lorraine N. Clark et al. · Annals of Neurology · 2010 · 120 citations