Gabriele Büchel

Association with Aurora-A Controls N-MYC-Dependent Promoter Escape and Pause Release of RNA Polymerase II during the Cell Cycle

Gabriele Büchel, Anne Carstensen, Ka-Yan Mak et al. · Cell Reports · 2017 · 109 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

Recruitment of BRCA1 limits MYCN-driven accumulation of stalled RNA polymerase

Steffi Herold, Jacqueline Kalb, Gabriele Büchel et al. · Nature · 2019 · 109 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +14

Combined inhibition of Aurora-A and ATR kinases results in regression of MYCN-amplified neuroblastoma

Isabelle Roeschert, Evon Poon, Anton G. Henssen et al. · Nature Cancer · 2021 · 105 citations · Full text

Medicine, Cancer Biology, Oncology +9

LRP8‐mediated selenocysteine uptake is a targetable vulnerability in MYCN‐amplified neuroblastoma

Hamed Alborzinia, Zhiyi Chen, Umut Yildiz et al. · EMBO Molecular Medicine · 2023 · 76 citations · Full text

Medicine, Cancer Biology, Oncology +14

MiR-205-driven downregulation of cholesterol biosynthesis through SQLE-inhibition identifies therapeutic vulnerability in aggressive prostate cancer

Charis Kalogirou, Johannes Linxweiler, Philipp Schmucker et al. · Nature Communications · 2021 · 75 citations · Full text

Life Sciences, Molecular Biology, Oncology +17